Life can be stressful without ATR.

O'Driscoll, Mark (2009) Life can be stressful without ATR. Nature Genetics, 41 (8). pp. 866-888. ISSN 10614036

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A new study reports the first mouse model for ATR-mutated Seckel syndrome. The mice show phenotypes recapitulating the human disorder and provide insights into how reduced ATR function affects normal embryonic development by increasing replicative stress, ultimately resulting in an accelerated aging phenotype postnatally. © 2009 Nature America, Inc. All rights reserved.

Item Type: Article
Schools and Departments: School of Life Sciences > Sussex Centre for Genome Damage and Stability
Depositing User: Mark O'Driscoll
Date Deposited: 06 Feb 2012 19:48
Last Modified: 24 Jul 2012 08:21
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