Main, Ewan (2005) A recurring theme in protein engineering: the design, stability and folding of repeat proteins. Current Opinion in Structural Biology, 15 (4). pp. 464-71. ISSN 0959440X

Full text not available from this repository.

Abstract

Repeat proteins are ubiquitous and are involved in a myriad of essential processes. They are typically non-globular structures that act as diverse scaffolds for the mediation of protein-protein interactions. These excitingly different structures, which arise from tandem arrays of a repeated structural motif, have generated significant interest with respect to protein engineering and design. Recent advances have been made in the design and characterisation of repeat proteins. The highlights include re-engineering of binding specificity, quantitative models of repeat protein stability and kinetic studies of repeat protein folding.

Item Type:	Article
Schools and Departments:	School of Life Sciences > Chemistry
Depositing User:	Ewan Main
Date Deposited:	06 Feb 2012 19:44
Last Modified:	31 May 2012 15:59
URI:	http://sro.sussex.ac.uk/id/eprint/21953

📧 Request an update