Bowler, Andrew, Dinsmore, Andrew, Doyle, Paul M and Young, Douglas W (1997) Synthesis of agonists and atagonists for central glutamate receptors by a novel 'ring switching' strategy. Journal of the Chemical Society, Perkin Transactions 1, 9. 1297 - 1306. ISSN 0300-922X
Full text not available from this repository.Abstract
A novel and versatile ring switching strategy has been developed for the synthesis of compounds with structural features consistent with activity at glutamate receptors. A variety of homochiral L-alanine derivatives substituted at the β-carbon atom with planar five and six-membered heteroaromatic rings have been prepared in a one- or two-pot reaction using this strategy and some of the products have been shown to have biological activity at central glutamate receptors.
Item Type: | Article |
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Schools and Departments: | School of Life Sciences > Chemistry |
Depositing User: | EPrints Services |
Date Deposited: | 06 Feb 2012 19:36 |
Last Modified: | 06 Jun 2013 11:49 |
URI: | http://sro.sussex.ac.uk/id/eprint/21440 |