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XPD structure reveals its secrets

journal contribution
posted on 2023-06-07, 14:56 authored by Alan LehmannAlan Lehmann
The XPD protein is central to our understanding of the relationship between NER deficiencies and human disorders. Three recent papers report the crystal structures of XPD from archaea. Apart from anticipated helicase domains the structures reveal a 4FeS cluster and novel "Arch" domain. The structures help our understanding of genotype-phenotype relationships in the XPD gene.

History

Publication status

  • Published

Journal

DNA Repair

ISSN

1568-7864

Publisher

Elsevier

Issue

11

Volume

7

Page range

1912-1915

Department affiliated with

  • Sussex Centre for Genome Damage Stability Publications

Notes

On Endnotes Ref: GDSC262

Full text available

  • No

Peer reviewed?

  • Yes

Legacy Posted Date

2009-02-23

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