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The molecular elements that underlie developmental evolution

journal contribution
posted on 2023-06-07, 23:15 authored by Claudio AlonsoClaudio Alonso, Adam S Wilkins
Abundant evidence indicates that developmental evolution, the foundation of morphological evolution, is based on changes in gene function. Over the past decade a consensus has developed that transcriptional regulation, acting through enhancer sequences, is the primary level of evolutionary significant change. Here we propose that other regulatory levels are probably as important as enhancers in developmental evolution. We also explain why these alternative regulatory levels might have been neglected, and briefly discuss ways to test our hypothesis.

History

Publication status

  • Published

Journal

Nature Reviews Genetics

ISSN

1471-0064

Volume

6

Page range

709-715

Pages

7.0

Department affiliated with

  • Evolution, Behaviour and Environment Publications

Notes

In this work I have conceived a new theoretical framework to investigate the mechanisms of developmental evolution. I initiated the research question, i.e. what is the spectrum of molecular modules underlying developmental evolution? - collected all data to address the question, co-analysed the data and co-wrote the paper.

Full text available

  • No

Peer reviewed?

  • Yes

Legacy Posted Date

2012-02-06

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