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The genomic rate of adaptive evolution

journal contribution
posted on 2023-06-07, 23:05 authored by Adam Eyre-WalkerAdam Eyre-Walker
The role of positive darwinian selection in evolution at the molecular level has been keenly debated for many years, with little resolution. However, a recent increase in DNA sequence data and the development of new methods of analysis have finally made this question tractable. Here, I review the current state-of-play of the field. Initial estimates in Drosophila suggest that 50% of all amino acid substitutions, and a substantial fraction of substitutions in non-coding DNA, have been fixed as a consequence of adaptive evolution. Estimates in microorganisms are even higher. By contrast, there is little evidence of widespread adaptive evolution in our own species

History

Publication status

  • Published

Journal

Trends in Ecology and Evolution

ISSN

0169-5347

Publisher

Elsevier

Issue

10

Volume

21

Page range

569-575

Pages

7.0

Department affiliated with

  • Evolution, Behaviour and Environment Publications

Full text available

  • No

Peer reviewed?

  • Yes

Legacy Posted Date

2012-02-06

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