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How do Rab proteins function in membrane traffic?
journal contribution
posted on 2023-06-07, 21:00 authored by John ArmstrongThe Rabs are a group of GTP-binding proteins implicated for some time in the targeting of different transport vesicles within the cell, but it has been unclear how they function, or how they relate to a second group of targeting proteins, the SNAREs. Recent work, discussed in this review, has used biophysical, biochemical and genetic approaches to begin to answer these questions for Rab3, Rab5 and the yeast protein Sec4p. However, the results from these three Rabs lead to a surprising conclusion: the different Rabs seem to function via highly diverse target proteins
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Publication status
- Published
Journal
International Journal of Biochemistry and Cell BiologyISSN
1357-2725Publisher
ElsevierExternal DOI
Issue
3Volume
32Page range
303-307Department affiliated with
- Biochemistry Publications
Full text available
- No
Peer reviewed?
- Yes
Legacy Posted Date
2012-02-06Usage metrics
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