Powell, M J and Watts, F Z (1990) Isolation of a gene encoding a mitochondrial HSP70 protein from Schizosaccharomyces pombe. Gene, 95 (1). pp. 105-110. ISSN 03781119

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Abstract

We have isolated cDNA and genomic clones encoding a mitochondrial HSP70 protein from Schizosaccharomyces pombe. Nucleotide sequence analysis indicates that the encoded protein is homologous to the HSP70s of other organisms. The highest degree of amino acid conservation is with the proteins encoded by the Escherichia coli dnaK gene, the SSC1 gene of Saccharomyces cerevisiae and the MTP70 gene of Trypanosoma cruzi, the latter two having recently been shown to be located in the mitochondria. Wester-blot analysis with immunoglobulin G raised against a peptide corresponding to the C terminus of the SSP1 protein indicates a 70-kDa protein which is associated with the mitochondria

Item Type:	Article
Schools and Departments:	School of Life Sciences > Sussex Centre for Genome Damage and Stability
Depositing User:	Felicity Watts
Date Deposited:	06 Feb 2012 18:30
Last Modified:	29 Mar 2012 11:17
URI:	http://sro.sussex.ac.uk/id/eprint/16803

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