The antisaccade task as a research tool in psychopathology: A critical review

Hutton, Samuel and Ettinger, Ulrich (2006) The antisaccade task as a research tool in psychopathology: A critical review. Psychophysiology, 43 (3). pp. 302-13. ISSN 0048-5772

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The antisaccade task is a measure of volitional control of behavior sensitive to fronto-striatal dysfunction. Here we outline important issues concerning antisaccade methodology, consider recent evidence of the cognitive processes and neural mechanisms involved in task performance, and review how the task has been applied to study psychopathology. We conclude that the task yields reliable and sensitive measures of the processes involved in resolving the conflict between volitional and reflexive behavioral responses, a key cognitive deficit relevant to a number of neuropsychiatric conditions. Additionally, antisaccade deficits may reflect genetic liability for schizophrenia. Finally, the ease and accuracy with which the task can be administered, combined with its sensitivity to fronto-striatal dysfunction and the availability of suitable control conditions, may make it a useful benchmark tool for studies of potential cognitive enhancers.

Item Type: Article
Schools and Departments: School of Psychology > Psychology
Depositing User: Samuel Hutton
Date Deposited: 06 Feb 2012 15:32
Last Modified: 03 Jul 2019 01:23

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