University of Sussex
Browse
Developing World Bioethics - 2022 - Seralegne - Composition and capacity of Institutional Review Boards and challenges.pdf (986.35 kB)

Composition and capacity of Institutional Review Boards, and challenges experienced by members in ethics review processes in Addis Ababa, Ethiopia: An exploratory qualitative study

Download (986.35 kB)
journal contribution
posted on 2023-06-10, 07:04 authored by Yemisrach Z Seralegne, Cynthia K Wangamati, Rosemarie D L C Bernabe, Bobbie FarsidesBobbie Farsides, Abraham Aseffa, Martha Zewdie
Few studies in sub-Saharan Africa evaluate Institutional Review Boards (IRBs) capacity. The study aims to explore the composition of IRBs, training, and challenges experienced in the ethics review processes by members of research institutions and universities in Addis Ababa, Ethiopia. Our findings indicate that most IRBs members were trained on research ethics and good clinical practice. However, majority perceived the trainings as basic. IRB members faced several challenges including: investigators wanting rapid review; time pressure; investigators not following checklists; limited expertise in reviewing clinical trials, studies on genetics, and traditional medicine; lack of IRB offices for administrative work; competing tasks; limited staffing and the lack of a standardized review system. There is need for advanced training on research ethics to meet the evolving research needs. In addition, investments in IRBs are needed in terms of funding, and physical and human resources in Addis Ababa and Ethiopia in general.

History

Publication status

  • Published

File Version

  • Published version

Journal

Developing World Bioethics

ISSN

1471-8731

Publisher

Wiley

Issue

1

Volume

23

Page range

50-58

Event location

England

Department affiliated with

  • Clinical and Experimental Medicine Publications

Full text available

  • Yes

Peer reviewed?

  • Yes

Legacy Posted Date

2023-05-18

First Open Access (FOA) Date

2023-05-18

First Compliant Deposit (FCD) Date

2023-05-18

Usage metrics

    University of Sussex (Publications)

    Categories

    No categories selected

    Licence

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC