May the 4Cs be with you an overview of complexity-inspired frameworks for analysing resting-state neuroimaging data.pdf (1.28 MB)
May the 4C's be with you: an overview of complexity-inspired frameworks for analysing resting-state neuroimaging data
journal contribution
posted on 2023-06-10, 06:22 authored by Fran Hancock, Fernando Ernesto Rosas De AndracaFernando Ernesto Rosas De Andraca, Pedro A M Mediano, Andrea I Luppi, Joanna Cabral, Ottavia Dipasquale, Federico E TurkheimerCompeting and complementary models of resting-state brain dynamics contribute to our phenomenological and mechanistic understanding of whole-brain coordination and communication, and provide potential evidence for differential brain functioning associated with normal and pathological behaviour. These neuroscientific theories stem from the perspectives of physics, engineering, mathematics and psychology and create a complicated landscape of domain-specific terminology and meaning, which, when used outside of that domain, may lead to incorrect assumptions and conclusions within the neuroscience community. Here, we review and clarify the key concepts of connectivity, computation, criticality and coherence-the 4C's-and outline a potential role for metastability as a common denominator across these propositions. We analyse and synthesize whole-brain neuroimaging research, examined through functional magnetic imaging, to demonstrate that complexity science offers a principled and integrated approach to describe, and potentially understand, macroscale spontaneous brain functioning.
History
Publication status
- Published
File Version
- Published version
Journal
Journal of the Royal Society InterfaceISSN
1742-5689Publisher
The Royal SocietyExternal DOI
Issue
191Volume
19Page range
1-14Event location
EnglandDepartment affiliated with
- Informatics Publications
Full text available
- Yes
Peer reviewed?
- Yes