File(s) under permanent embargo
Agreement between self-reported and objective measures of sleep in people with HIV and lifestyle-similar HIV-negative individuals
journal contribution
posted on 2023-06-10, 04:52 authored by Davide De Francesco, Caroline A Sabin, Alan Winston, Patrick W G Mallon, Jane Anderson, Marta Boffito, Nicki D Doyle, Lewis Haddow, Frank A Post, Jaime Vera RojasJaime Vera Rojas, Memory Sachikonye, Susan Redline, Ken M KunisakiObjectives: The aim of this study was to evaluate the agreement between self-reported sleep measures and insomnia with objectively measured sleep parameters in people with HIV (PWH) and HIV-negative individuals. Design: A cross-sectional analysis of PWH and lifestyle-similar HIV-negative individuals. Methods: Self-reported measures included time spent in bed, sleep onset latency and a validated insomnia questionnaire. Objective measures were assessed via 7-days/nights of actigraphy data to determine average and intra-individual variability of several sleep measures (including time spent in bed and onset latency). Spearman's correlation coefficient and Cohen's ? were used to assess the agreement between self-reported and actigraphy-assessed measures. Associations between insomnia and actigraphy-assessed sleep parameters were evaluated using partial least-square discriminant analysis (PLS-DA). Results: We found fair correlation between self-reported and actigraphy-assessed time spent in bed in 342 PWH (rs = 0.46) and 119 HIV-negative individuals (rs = 0.48). Among PWH, the correlation did not differ by age, education, depressive symptoms and self-reported insomnia (all P > 0.05), but was stronger in men (P = 0.05) and in those with a BMI of at least 25 kg/m2 (P < 0.001). Agreement between self-reported and actigraphy-assessed sleep onset latency was poor in both PWH (? = 0.002, P = 0.49) and HIV-negative individuals (? = 0.009, P = 0.65). According to PLS-DA, self-reported insomnia most strongly correlated with intra-individual variability of sleep duration, movement index and efficiency. Conclusion: We report poor-to-fair agreement between self-reported and actigraphy-assessed sleep measures in PWH. Insomnia symptoms correlated with regularity of sleep duration, quality and efficiency. These findings highlight the importance of both patient-reported and objective measures of daily sleep variation, for better understanding sleep disorders in PWH.
History
Publication status
- Published
File Version
- Published version
Journal
AIDSISSN
0269-9370Publisher
Ovid Technologies (Wolters Kluwer Health)External DOI
Issue
7Volume
35Page range
1051-1060Event location
EnglandDepartment affiliated with
- Global Health and Infection Publications
Full text available
- No
Peer reviewed?
- Yes
Legacy Posted Date
2022-09-28First Compliant Deposit (FCD) Date
2022-09-27Usage metrics
Categories
No categories selectedLicence
Exports
RefWorks
BibTeX
Ref. manager
Endnote
DataCite
NLM
DC