del Río, Magdalena, Racey, Chris, Ren, Zhiting, Qiu, Jiang, Wang, Hao-Ting and Ward, Jamie (2022) Higher sensory sensitivity is linked to greater expansion amongst functional connectivity gradients. Journal of Autism and Developmental Disorders. pp. 1-19. ISSN 0162-3257

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Abstract

Insofar as the autistic-like phenotype presents in the general population, it consists of partially dissociable traits, such as social and sensory issues. Here, we investigate individual differences in cortical organisation related to autistic-like traits. Connectome gradient decomposition based on resting state fMRI data reliably reveals a principal gradient spanning from unimodal to transmodal regions, reflecting the transition from perception to abstract cognition. In our non-clinical sample, this gradient's expansion, indicating less integration between visual and default mode networks, correlates with subjective sensory sensitivity (measured using the Glasgow Sensory Questionnaire, GSQ), but not other autistic-like traits (measured using the Autism Spectrum Quotient, AQ). This novel brain-based correlate of the GSQ demonstrates sensory issues can be disentangled from the wider autistic-like phenotype.

Item Type:	Article
Schools and Departments:	School of Psychology > Psychology
SWORD Depositor:	Mx Elements Account
Depositing User:	Mx Elements Account
Date Deposited:	27 Sep 2022 10:33
Last Modified:	02 Nov 2022 15:45
URI:	http://sro.sussex.ac.uk/id/eprint/108154

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