University of Sussex
Browse
s10803-022-05772-z.pdf (1.41 MB)

Higher sensory sensitivity is linked to greater expansion amongst functional connectivity gradients

Download (1.41 MB)
journal contribution
posted on 2023-06-10, 04:51 authored by Magdalena del Río, Chris Racey, Zhiting Ren, Jiang Qiu, Hao-Ting Wang, Jamie WardJamie Ward
Insofar as the autistic-like phenotype presents in the general population, it consists of partially dissociable traits, such as social and sensory issues. Here, we investigate individual differences in cortical organisation related to autistic-like traits. Connectome gradient decomposition based on resting state fMRI data reliably reveals a principal gradient spanning from unimodal to transmodal regions, reflecting the transition from perception to abstract cognition. In our non-clinical sample, this gradient's expansion, indicating less integration between visual and default mode networks, correlates with subjective sensory sensitivity (measured using the Glasgow Sensory Questionnaire, GSQ), but not other autistic-like traits (measured using the Autism Spectrum Quotient, AQ). This novel brain-based correlate of the GSQ demonstrates sensory issues can be disentangled from the wider autistic-like phenotype.

History

Publication status

  • Published

File Version

  • Published version

Journal

Journal of Autism and Developmental Disorders

ISSN

0162-3257

Publisher

Springer Nature

Page range

1-19

Department affiliated with

  • Psychology Publications

Full text available

  • Yes

Peer reviewed?

  • Yes

Legacy Posted Date

2022-09-27

First Open Access (FOA) Date

2022-11-02

First Compliant Deposit (FCD) Date

2022-09-26

Usage metrics

    University of Sussex (Publications)

    Categories

    No categories selected

    Licence

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC