s10803-022-05772-z.pdf (1.41 MB)
Higher sensory sensitivity is linked to greater expansion amongst functional connectivity gradients
journal contribution
posted on 2023-06-10, 04:51 authored by Magdalena del Río, Chris Racey, Zhiting Ren, Jiang Qiu, Hao-Ting Wang, Jamie WardJamie WardInsofar as the autistic-like phenotype presents in the general population, it consists of partially dissociable traits, such as social and sensory issues. Here, we investigate individual differences in cortical organisation related to autistic-like traits. Connectome gradient decomposition based on resting state fMRI data reliably reveals a principal gradient spanning from unimodal to transmodal regions, reflecting the transition from perception to abstract cognition. In our non-clinical sample, this gradient's expansion, indicating less integration between visual and default mode networks, correlates with subjective sensory sensitivity (measured using the Glasgow Sensory Questionnaire, GSQ), but not other autistic-like traits (measured using the Autism Spectrum Quotient, AQ). This novel brain-based correlate of the GSQ demonstrates sensory issues can be disentangled from the wider autistic-like phenotype.
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Publication status
- Published
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- Published version
Journal
Journal of Autism and Developmental DisordersISSN
0162-3257Publisher
Springer NatureExternal DOI
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1-19Department affiliated with
- Psychology Publications
Full text available
- Yes
Peer reviewed?
- Yes
Legacy Posted Date
2022-09-27First Open Access (FOA) Date
2022-11-02First Compliant Deposit (FCD) Date
2022-09-26Usage metrics
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