Mutations in CRBN and other cereblon pathway genes are infrequently associated with acquired resistance to immunomodulatory drugs

Jones, John; Barber, A; Le Bihan, Y V; Weinhold, N; Ashby, C; Walker, B A; Wardell, C P; Wang, H; Kaiser, M F; Jackson, G H; Davies, F E; Chopra, R; Morgan, G J; Pawlyn, C

s41375-021-01373-4.pdf (960.73 kB)

Mutations in CRBN and other cereblon pathway genes are infrequently associated with acquired resistance to immunomodulatory drugs

journal contribution

posted on 2023-06-10, 02:19 authored by John JonesJohn Jones, A Barber, Y V Le Bihan, N Weinhold, C Ashby, B A Walker, C P Wardell, H Wang, M F Kaiser, G H Jackson, F E Davies, R Chopra, G J Morgan, C Pawlyn

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History

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Published

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Published version

Journal

Leukemia

ISSN

0887-6924

Publisher

Springer Nature

External DOI

https://doi.org/10.1038/s41375-021-01373-4

Volume

35

Page range

3017-3020

Event location

England

Department affiliated with

Clinical and Experimental Medicine Publications

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Yes

Peer reviewed?

Yes

Legacy Posted Date

2022-01-17

First Open Access (FOA) Date

2022-01-17

First Compliant Deposit (FCD) Date

2022-01-17

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Keywords

Adaptor Proteins Signal Transducing Biomarkers Tumor Drug Resistance Neoplasm Humans Immunomodulating Agents Multiple Myeloma Mutation Ubiquitin-Protein Ligases

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CC BY 4.0

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Mutations in CRBN and other cereblon pathway genes are infrequently associated with acquired resistance to immunomodulatory drugs

History

Publication status

File Version

Journal

ISSN

Publisher

External DOI

Volume

Page range

Event location

Department affiliated with

Full text available

Peer reviewed?

Legacy Posted Date

First Open Access (FOA) Date

First Compliant Deposit (FCD) Date

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Keywords

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