Ancestral circuits for vertebrate color vision emerge at the first retinal synapse.pdf (7.59 MB)
Ancestral circuits for vertebrate color vision emerge at the first retinal synapse
journal contribution
posted on 2023-06-10, 01:38 authored by Takeshi YoshimatsuTakeshi Yoshimatsu, Philipp Bartel, Cornelius Schröder, Filip JaniakFilip Janiak, François St-Pierre, Philipp Berens, Thomas BadenThomas BadenFor color vision, retinal circuits separate information about intensity and wavelength. In vertebrates that use the full complement of four “ancestral” cone types, the nature and implementation of this computation remain poorly understood. Here, we establish the complete circuit architecture of outer retinal circuits underlying color processing in larval zebrafish. We find that the synaptic outputs of red and green cones efficiently rotate the encoding of natural daylight in a principal components analysis–like manner to yield primary achromatic and spectrally opponent axes, respectively. Blue cones are tuned to capture most remaining variance when opposed to green cones, while UV cone present a UV achromatic axis for prey capture. We note that fruitflies use essentially the same strategy. Therefore, rotating color space into primary achromatic and chromatic axes at the eye’s first synapse may thus be a fundamental principle of color vision when using more than two spectrally well-separated photoreceptor types.
Funding
Anisotropic retinal circuits for processing of colour and space in nature; G2397; BBSRC-BIOTECHNOLOGY & BIOLOGICAL SCIENCES RESEARCH COUNCIL; BB/R014817/1
How to connect an eye to a brain; G3137; WELLCOME TRUST; WT Ref: 220277/
EMBO Young Investigator Programme; G2920; EMBO-EUROPEAN MOLECULAR BIOLOGY ORGANIZATION; Baden
Philip Leverhulme Prize - Biological Sciences; G2276; LEVERHULME TRUST; PLP-2017-005
Anisotropic retinal circuits for processing of colour and space in nature - Lister Institute Research Prize; G2503; LISTER INSTITUTE
NeuroVisEco - Zebrafish vision in its natural context: from natural scenes through retinal and central processing to behaviour; G1871; EUROPEAN UNION; 677687
History
Publication status
- Published
File Version
- Published version
Journal
Science AdvancesISSN
2375-2548Publisher
American Association for the Advancement of ScienceExternal DOI
Issue
42Volume
7Page range
1-18Event location
United StatesDepartment affiliated with
- Neuroscience Publications
Full text available
- Yes
Peer reviewed?
- Yes
Legacy Posted Date
2021-11-04First Open Access (FOA) Date
2021-11-04First Compliant Deposit (FCD) Date
2021-11-03Usage metrics
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