Sussex Research Online: No conditions. Results ordered -Date Deposited. http://sro.sussex.ac.uk/ http://sro.sussex.ac.uk/images/sitelogo.png Sussex Research Online: No conditions. Results ordered -Date Deposited. http://sro.sussex.ac.uk/ Mon, 20 Nov 2023 04:17:26 +0000 Mon, 20 Nov 2023 04:17:26 +0000 en Fri, 13 Jan 2023 12:09:41 +0000 The deubiquitinase (DUB) USP13 promotes Mcl-1 stabilisation in cervical cancer http://sro.sussex.ac.uk/id/eprint/110122/ http://sro.sussex.ac.uk/id/eprint/110122/ Morgan, Ethan L, Patterson, Molly R, Barba-Moreno, Diego, Scarth, James A, Wilson, Adam and Macdonald, Andrew (2021) The deubiquitinase (DUB) USP13 promotes Mcl-1 stabilisation in cervical cancer. Oncogene, 40. pp. 2112-2129. ISSN 0950-9232 Wed, 13 Apr 2022 07:48:43 +0100 PDGF-R inhibition induces glioblastoma cell differentiation via DUSP1/p38MAPK signalling http://sro.sussex.ac.uk/id/eprint/105298/ http://sro.sussex.ac.uk/id/eprint/105298/ Lane, Rosemary, Cilibrasi, Chiara, Chen, Jianing, Shah, Kalpit, Messuti, Eleonora, Mazarakis, Nektarios K, Stebbing, Justin, Critchley, Giles, Song, Erwei, Simon, Thomas and Giamas, Georgios (2022) PDGF-R inhibition induces glioblastoma cell differentiation via DUSP1/p38MAPK signalling. Oncogene. pp. 1-15. ISSN 0950-9232 Fri, 10 Sep 2021 13:14:07 +0100 MNK1 and MNK2 enforce expression of E2F1, FOXM1, and WEE1 to drive soft tissue sarcoma http://sro.sussex.ac.uk/id/eprint/101628/ http://sro.sussex.ac.uk/id/eprint/101628/ Ke, Xin-Yu, Chen, Ye, Tham, Valarie Yu-Yan, Lin, Ruby Yu-Tong, Dakle, Pushkar, Nacro, Kassoum, Puhaindran, Mark Edward, Houghton, Peter, Pang, Angela, Lee, Victor Kwanmin, Ding, Ling-Wen, Gery, Sigal, Hill, Jeffrey, Chen, Leilei, Xu, Liang and Koeffler, H Phillip (2021) MNK1 and MNK2 enforce expression of E2F1, FOXM1, and WEE1 to drive soft tissue sarcoma. Oncogene, 40 (10). pp. 1851-1867. ISSN 0950-9232 Tue, 08 Sep 2020 07:25:42 +0100 Androgen receptor signaling regulates the transcriptome of prostate cancer cells by modulating global alternative splicing http://sro.sussex.ac.uk/id/eprint/93610/ http://sro.sussex.ac.uk/id/eprint/93610/ Shah, Kalpit, Gagliano, Teresa, Garland, Lisa, O’Hanlon, Timothy, Bortolotti, Daria, Gentili, Valentina, Rizzo, Roberta, Giamas, Georgios and Dean, Michael (2020) Androgen receptor signaling regulates the transcriptome of prostate cancer cells by modulating global alternative splicing. Oncogene. ISSN 0950-9232 Thu, 07 May 2020 07:07:26 +0100 Breaking through the glioblastoma micro-environment via extracellular vesicles http://sro.sussex.ac.uk/id/eprint/91186/ http://sro.sussex.ac.uk/id/eprint/91186/ Simon, Thomas, Jackson, Ellen and Giamas, Georgios (2020) Breaking through the glioblastoma micro-environment via extracellular vesicles. Oncogene. pp. 1-14. ISSN 0950-9232 Fri, 20 Dec 2019 11:38:05 +0000 Wnt addiction of genetically defined cancers reversed by PORCN inhibition http://sro.sussex.ac.uk/id/eprint/88930/ http://sro.sussex.ac.uk/id/eprint/88930/ Madan, B, Ke, Z, Harmston, N, Ho, S Y, Frois, A O, Alam, J, Jeyaraj, D A, Pendharkar, V, Ghosh, K, Virshup, I H, Manoharan, V, Ong, E H Q, Sangthongpitag, K, Hill, J, Petretto, E and others, (2016) Wnt addiction of genetically defined cancers reversed by PORCN inhibition. Oncogene, 35. pp. 2197-2207. ISSN 0950-9232 Fri, 15 Jun 2018 08:57:04 +0100 Genomic modelling of the ESR1 Y537S mutation for evaluating function and new therapeutic approaches for metastatic breast cancer http://sro.sussex.ac.uk/id/eprint/76518/ http://sro.sussex.ac.uk/id/eprint/76518/ Harrod, A, Fulton, J, Nguyen, V T M, Periyasamy, M, Ramos-Garcia, L, Lai, C-F, Metodieva, G, de Giorgio, A, Williams, R L, Santos, D B, Gomez, P J, Lin, M-L, Metodiev, M V, Stebbing, J, Castellano, L, Magnani, L, Coombes, R C, Buluwela, L and Ali, S (2017) Genomic modelling of the ESR1 Y537S mutation for evaluating function and new therapeutic approaches for metastatic breast cancer. Oncogene, 36 (16). pp. 2286-2296. ISSN 1476-5594 Fri, 15 Jun 2018 08:39:07 +0100 Novel tumour suppressive protein encoded by circular RNA, circ-SHPRH, in glioblastomas http://sro.sussex.ac.uk/id/eprint/76515/ http://sro.sussex.ac.uk/id/eprint/76515/ Begum, S, Yiu, A, Stebbing, J and Castellano, L (2018) Novel tumour suppressive protein encoded by circular RNA, circ-SHPRH, in glioblastomas. Oncogene, 37. pp. 4055-4057. ISSN 1476-5594 Mon, 19 Mar 2018 12:18:24 +0000 LMTK3 confers chemo-resistance in breast cancer http://sro.sussex.ac.uk/id/eprint/74487/ http://sro.sussex.ac.uk/id/eprint/74487/ Stebbing, Justin, Shah, Kalpit, Lit, Lei Cheng, Gagliano, Teresa, Ditsiou, Angeliki, Wang, Tingting, Wendler, Franz, Simon, Thomas, Szabo, Krisztina Sára, O’Hanlon, Timothy, Dean, Michael, Roslani, April Camilla, Cheah, Swee Hung, Lee, Soo-Chin and Giamas, Georgios (2018) LMTK3 confers chemo-resistance in breast cancer. Oncogene, 37 (23). pp. 3113-3130. ISSN 1476-5594 Fri, 26 Aug 2016 14:35:47 +0100 Extracellular vesicles swarm the cancer microenvironment: from tumor–stroma communication to drug intervention http://sro.sussex.ac.uk/id/eprint/63032/ http://sro.sussex.ac.uk/id/eprint/63032/ Wendler, F, Favicchio, R, Simon, T, Alifrangis, C, Stebbing, J and Giamas, G (2017) Extracellular vesicles swarm the cancer microenvironment: from tumor–stroma communication to drug intervention. Oncogene, 36 (7). pp. 877-884. ISSN 0950-9232 Wed, 04 Nov 2015 11:27:35 +0000 Targeting tumor-stroma crosstalk: the example of the NT157 inhibitor http://sro.sussex.ac.uk/id/eprint/57526/ http://sro.sussex.ac.uk/id/eprint/57526/ Rampias, T, Favicchio, R, Stebbing, J and Giamas, G (2016) Targeting tumor-stroma crosstalk: the example of the NT157 inhibitor. Oncogene, 35 (20). pp. 2562-2564. ISSN 0950-9232 Tue, 07 Jul 2015 10:10:15 +0100 The regulatory roles of phosphatases in cancer http://sro.sussex.ac.uk/id/eprint/55202/ http://sro.sussex.ac.uk/id/eprint/55202/ Stebbing, J, Lit, L C, Zhang, H, Darrington, R S, Melaiu, O, Rudraraju, B and Giamas, G (2014) The regulatory roles of phosphatases in cancer. Oncogene, 33 (8). pp. 939-953. ISSN 1476-5594 Tue, 07 Jul 2015 09:01:53 +0100 KSR1 regulates BRCA1 degradation and inhibits breast cancer growth http://sro.sussex.ac.uk/id/eprint/55208/ http://sro.sussex.ac.uk/id/eprint/55208/ Stebbing, J, Zhang, H, Xu, Y, Lit, L C, Green, A R, Grothey, A, Lombardo, Y, Periyasamy, M, Blighe, K, Zhang, W, Shaw, J A, Ellis, I O, Lenz, H J and Giamas, G (2015) KSR1 regulates BRCA1 degradation and inhibits breast cancer growth. Oncogene, 34 (16). pp. 2103-2114. ISSN 1476-5594 Tue, 07 Jul 2015 08:11:21 +0100 Claudin-1 as a promoter of EMT in hepatocellular carcinoma http://sro.sussex.ac.uk/id/eprint/55200/ http://sro.sussex.ac.uk/id/eprint/55200/ Stebbing, J, Filipović, A and Giamas, G (2013) Claudin-1 as a promoter of EMT in hepatocellular carcinoma. Oncogene, 32 (41). pp. 4871-4872. ISSN 0950-9232 Tue, 07 Jul 2015 07:58:09 +0100 LMTK3 is implicated in endocrine resistance via multiple signaling pathways http://sro.sussex.ac.uk/id/eprint/55197/ http://sro.sussex.ac.uk/id/eprint/55197/ Stebbing, J, Filipovic, A, Lit, L C, Blighe, K, Grothey, A, Xu, Y, Miki, Y, Chow, L W, Coombes, R C, Sasano, H, Shaw, J A and Giamas, G (2013) LMTK3 is implicated in endocrine resistance via multiple signaling pathways. Oncogene, 32 (28). pp. 3371-3380. ISSN 0950-9232 Thu, 05 Mar 2015 08:47:47 +0000 Restricting direct interaction of CDC37 with HSP90 does not compromise chaperoning of client proteins http://sro.sussex.ac.uk/id/eprint/53206/ http://sro.sussex.ac.uk/id/eprint/53206/ Smith, J R, de Billy, E, Hobbs, S, Powers, M, Prodromou, C, Pearl, L, Clarke, P A and Workman, P (2013) Restricting direct interaction of CDC37 with HSP90 does not compromise chaperoning of client proteins. Oncogene, 34 (1). pp. 15-26. ISSN 0950-9232 Fri, 02 Nov 2012 16:49:49 +0000 An siRNA screen identifies RSK1 as a key modulator of lung cancer metastasis http://sro.sussex.ac.uk/id/eprint/42059/ http://sro.sussex.ac.uk/id/eprint/42059/ Lara, R, Mauri, F A, Taylor, H, Derua, R, Shia, A, Gray, C, Nicols, A, Shiner, R J, Schofield, E, Bates, P A, Waelkens, E, Dallman, M, Lamb, J, Zicha, D, Downward, J, Seckl, M J and Pardo, O E (2011) An siRNA screen identifies RSK1 as a key modulator of lung cancer metastasis. Oncogene, 30 (32). pp. 3513-3521. ISSN 1476-5594 Wed, 09 May 2012 09:52:36 +0100 Aberrant translational control of the c-myc gene in multiple myeloma. http://sro.sussex.ac.uk/id/eprint/38772/ http://sro.sussex.ac.uk/id/eprint/38772/ Paulin, F E, West, M J, Sullivan, N F, Whitney, R L, Lyne, L and Willis, A E (1996) Aberrant translational control of the c-myc gene in multiple myeloma. Oncogene, 13 (3). pp. 505-513. ISSN 0950-9232 Wed, 09 May 2012 09:46:37 +0100 Translational induction of the c-myc oncogene via activation of the FRAP/TOR signalling pathway. http://sro.sussex.ac.uk/id/eprint/38769/ http://sro.sussex.ac.uk/id/eprint/38769/ West, Michelle J, Stoneley, Mark and Willis, Anne E (1998) Translational induction of the c-myc oncogene via activation of the FRAP/TOR signalling pathway. Oncogene, 17 (6). pp. 769-780. ISSN 0950-9232 Thu, 03 May 2012 12:35:10 +0100 Translational upregulation of the c-myc oncogene in Bloom's syndrome cell lines. http://sro.sussex.ac.uk/id/eprint/38773/ http://sro.sussex.ac.uk/id/eprint/38773/ West, M J, Sullivan, N F and Willis, A E (1995) Translational upregulation of the c-myc oncogene in Bloom's syndrome cell lines. Oncogene, 11 (12). pp. 2515-2524. ISSN 0950-9232 Mon, 06 Feb 2012 21:08:40 +0000 Epstein-Barr virus exploits the normal cell pathway to regulate Rb activity during the immortalisation of primary B-cells http://sro.sussex.ac.uk/id/eprint/29754/ http://sro.sussex.ac.uk/id/eprint/29754/ Cannell, EJ, Farrell, PJ and Sinclair, AJ (1996) Epstein-Barr virus exploits the normal cell pathway to regulate Rb activity during the immortalisation of primary B-cells. Oncogene, 13 (7). pp. 1413-1421. ISSN 0950-9232 Mon, 06 Feb 2012 20:02:40 +0000 The life and death of DNA-PK http://sro.sussex.ac.uk/id/eprint/23701/ http://sro.sussex.ac.uk/id/eprint/23701/ Collis, Spencer J, DeWeese, Theodore L, Jeggo, Penny A and Parker, Antony R (2004) The life and death of DNA-PK. Oncogene, 24 (6). pp. 949-961. ISSN 1476-5594 Mon, 06 Feb 2012 19:51:40 +0000 Degradation of eukaryotic polypeptide chain initiation factor (eIF) 4G in response to induction of apoptosis in human lymphoma cell lines http://sro.sussex.ac.uk/id/eprint/22592/ http://sro.sussex.ac.uk/id/eprint/22592/ Clemens, Michael J, Bushell, Martin and Morley, Simon J (1998) Degradation of eukaryotic polypeptide chain initiation factor (eIF) 4G in response to induction of apoptosis in human lymphoma cell lines. Oncogene, 17 (22). pp. 2921-2931. ISSN 0950-9232 Mon, 06 Feb 2012 19:30:46 +0000 p27KIP1 is down-regulated by two different mechanisms in human lymphoid cells undergoing apoptosis http://sro.sussex.ac.uk/id/eprint/20947/ http://sro.sussex.ac.uk/id/eprint/20947/ Frost, V and Sinclair, AJ (2000) p27KIP1 is down-regulated by two different mechanisms in human lymphoid cells undergoing apoptosis. Oncogene, 19 (27). pp. 3115-3120. ISSN 0950-9232 Mon, 06 Feb 2012 18:29:35 +0000 Exploitation of a non-apoptotic caspase to regulate the abundance of the cdkl p27KIP1 in lymphoid cells http://sro.sussex.ac.uk/id/eprint/16713/ http://sro.sussex.ac.uk/id/eprint/16713/ Frost, V, Al-Mehairi, S and Sinclair, AJ (2001) Exploitation of a non-apoptotic caspase to regulate the abundance of the cdkl p27KIP1 in lymphoid cells. Oncogene, 20 (22). pp. 2737-2748. ISSN 0950-9232 Mon, 06 Feb 2012 18:15:45 +0000 EBV EBNA 2 stimulates CDK9-dependent transcription and RNA polymerase II phosphorylation on serine 5 http://sro.sussex.ac.uk/id/eprint/15480/ http://sro.sussex.ac.uk/id/eprint/15480/ Bark-Jones, S J, Webb, H M and West, M J (2006) EBV EBNA 2 stimulates CDK9-dependent transcription and RNA polymerase II phosphorylation on serine 5. Oncogene, 25 (12). pp. 1775-1785. ISSN 0950-9232 DNA double-strand breaks: their cellular and clinical impact? http://sro.sussex.ac.uk/id/eprint/1852/ http://sro.sussex.ac.uk/id/eprint/1852/ Jeggo, P A and Löbrich, M (2007) DNA double-strand breaks: their cellular and clinical impact? Oncogene, 26 (56). pp. 7717-7719. ISSN 0950-9232 Mitogenic synergy through multilevel convergence of hepatocyte growth factor and interleukin-4 signaling pathways http://sro.sussex.ac.uk/id/eprint/1058/ http://sro.sussex.ac.uk/id/eprint/1058/ Day, R. M., Soon, L., Breckenridge, D., Bridges, Bryn Arthur, Patel, B. K., Wang, L. M., Corey, S. J. and Bottaro, D. P. (2002) Mitogenic synergy through multilevel convergence of hepatocyte growth factor and interleukin-4 signaling pathways. Oncogene, 21 (14). pp. 2201-11. ISSN 0950-9232 Nbs1 promotes ATM dependent phosphorylation events including those required for G1/S arrest http://sro.sussex.ac.uk/id/eprint/1055/ http://sro.sussex.ac.uk/id/eprint/1055/ Girard, P-M., Riballo, E., Begg, A., Waugh, A. and Jeggo, P. A. (2002) Nbs1 promotes ATM dependent phosphorylation events including those required for G1/S arrest. Oncogene, 21. pp. 4191-4199. ISSN 0950-9232