http://sro.sussex.ac.uk/ http://sro.sussex.ac.uk/images/sitelogo.png http://sro.sussex.ac.uk/ Sat, 11 Nov 2023 17:36:52 +0000 Sat, 11 Nov 2023 17:36:52 +0000 en Tue, 21 Jun 2022 11:24:13 +0100 http://sro.sussex.ac.uk/id/eprint/106482/ http://sro.sussex.ac.uk/id/eprint/106482/ Sharp, Swee Y, Boxall, Kathy, Rowlands, Martin, Prodromou, Chrisostomos, Roe, S Mark, Maloney, Alison, Powers, Marissa, Clarke, Paul A, Box, Gary, Sanderson, Sharon, Patterson, Lisa, Matthews, Thomas P, Cheung, Kwai-Ming J, Ball, Karen, Pearl, Laurence and others, (2019) Correction: In vitro Biological Characterization of a Novel, Synthetic Diaryl Pyrazole Resorcinol Class of Heat Shock Protein 90 Inhibitors. Cancer Research, 79 (1). p. 287. ISSN 0008-5472 Thu, 12 Nov 2020 10:27:24 +0000 http://sro.sussex.ac.uk/id/eprint/95009/ http://sro.sussex.ac.uk/id/eprint/95009/ Zagorac, Sladjana, de Giorgio, Alex, Dabrowska, Aleksandra, Kalisz, Mark, Casas-Vila, Nuria, Cathcart, Paul, Yiu, Angela, Ottaviani, Silvia, Degani, Neta, Lombardo, Ylenia, Tweedie, Alistair, Nissan, Tracy, Vance, Keith W, Ulitsky, Igor, Stebbing, Justin and Castellano, Leandro (2020) SCIRT lncRNA restrains tumorigenesis by opposing transcriptional programs of tumor-initiating cells. Cancer Research. ISSN 0008-5472 Fri, 15 Jun 2018 12:00:16 +0100 http://sro.sussex.ac.uk/id/eprint/76532/ http://sro.sussex.ac.uk/id/eprint/76532/ Pinho, Filipa G, Frampton, Adam E, Nunes, Joao, Krell, Jonathan, Alshaker, Heba, Jacob, Jimmy, Pellegrino, Loredana, Roca-Alonso, Laura, de Giorgio, Alexander, Harding, Victoria, Waxman, Jonathan, Stebbing, Justin, Pchejetski, Dmitry and Castellano, Leandro (2013) Downregulation of microRNA-515-5p by the estrogen receptor modulates sphingosine kinase 1 and breast cancer cell proliferation. Cancer Research, 73 (19). pp. 5936-5948. ISSN 0008-5472 Wed, 20 Dec 2017 13:02:22 +0000 http://sro.sussex.ac.uk/id/eprint/72397/ http://sro.sussex.ac.uk/id/eprint/72397/ Rulten, Stuart and Caldecott, Keith (2016) The PARP inhibitor AZD2461 provides insights into the role of PARP3 inhibition for both synthetic lethality and tolerability with chemotherapy in preclinical models. Cancer Research, 76 (20). ISSN 0008-5472 Wed, 27 Apr 2016 10:01:35 +0100 http://sro.sussex.ac.uk/id/eprint/60629/ http://sro.sussex.ac.uk/id/eprint/60629/ Camp, N, Lin, W-Y, Bigelow, A, Burghel, G, Mosbruger, T, Parry, M A, Waller, R G, Rigas, S H, Tai, P-Y, Berrett, K, Rajamanickam, V, Cosby, R, Brock, I, Jones, B, Connely, D, Sargent, R, Wang, G, Factor, R, Bernard, P, Cannon-Albright, L, Kinght, S, Abo, R, Werner, T, Reed, M, Gertz, J and Cox, A (2016) Discordant Haplotype Sequencing Identifies Functional Variants at the 2q33 Breast Cancer Risk Locus. Cancer Research, 76 (8). pp. 1916-1925. ISSN 0008-5472 Wed, 30 Sep 2015 07:00:33 +0100 http://sro.sussex.ac.uk/id/eprint/56878/ http://sro.sussex.ac.uk/id/eprint/56878/ Caserta, Stefano, Alessi, Patrizia, Guarnerio, Jlenia, Basso, Veronica and Mondino, Anna (2008) Synthetic CD4+ T cell-targeted antigen-presenting cells elicit protective antitumor responses. Cancer Research, 68 (8). pp. 3010-3018. ISSN 0008-5472 Wed, 25 Feb 2015 09:54:53 +0000 http://sro.sussex.ac.uk/id/eprint/44376/ http://sro.sussex.ac.uk/id/eprint/44376/ Sharp, Swee Y, Boxall, Kathy, Rowlands, Martin, Prodromou, Chrisostomos, Roe, S Mark, Maloney, Alison, Powers, Marissa, Clarke, Paul A, Box, Gary, Sanderson, Sharon, Patterson, Lisa, Matthews, Thomas P, Cheung, Kwai-Ming J, Ball, Karen, Hayes, Angela, Raynaud, Florence, Marais, Richard, Pearl, Laurence, Eccles, Sue, Aherne, Wynne, McDonald, Edward and Workman, Paul (2007) In vitro biological characterization of a novel, synthetic diaryl pyrazole resorcinol class of heat shock protein 90 inhibitors. Cancer Research, 67 (5). pp. 2206-2216. ISSN 0008-5472 Thu, 01 Nov 2012 09:05:08 +0000 http://sro.sussex.ac.uk/id/eprint/41087/ http://sro.sussex.ac.uk/id/eprint/41087/ Syed, Nelofer, Coley, Helen M, Sehouli, Jalid, Koensgen, Dominique, Mustea, Alexander, Szlosarek, Peter, McNeish, Iain, Blagden, Sarah P, Schmid, Peter, Lovell, David P, Hatzimichael, Eleftheria and Crook, Tim (2011) Polo-like kinase Plk2 is an epigenetic determinant of chemosensitivity and clinical outcomes in ovarian cancer. Cancer Research, 71 (9). pp. 3317-3327. ISSN 0008-5472 Thu, 05 Jul 2012 09:25:58 +0100 http://sro.sussex.ac.uk/id/eprint/39932/ http://sro.sussex.ac.uk/id/eprint/39932/ Deckbar, Dorothee, Stiff, Thomas, Kock, Barbara, Reis, Caroline, Löbrich, Markus and Jeggo, Penny (2010) The limitations of the G1-S checkpoint. Cancer Research, 70 (11). pp. 4412-4421. ISSN 0008-5472 Tue, 24 Apr 2012 08:53:13 +0100 http://sro.sussex.ac.uk/id/eprint/38697/ http://sro.sussex.ac.uk/id/eprint/38697/ Tozer, Gillian M, Akerman, Simon, Cross, Neil A, Barber, Paul R, Björndahl, Meit A, Greco, Olga, Harris, Sheila, Hill, Sally A, Honess, Davina J, Ireson, Christopher R, Pettyjohn, Katie L, Prise, Vivien E, Reyes-Aldasoro, Constantino C, Ruhrberg, Christiana, Shima, David T and Kanthou, Chryso (2008) Blood Vessel Maturation and Response to Vascular-Disrupting Therapy in Single Vascular Endothelial Growth Factor-A Isoform–Producing Tumors. Cancer Research, 68 (7). pp. 2301-2311. ISSN 0008-5472 Mon, 06 Feb 2012 21:10:46 +0000 http://sro.sussex.ac.uk/id/eprint/29985/ http://sro.sussex.ac.uk/id/eprint/29985/ Anderson, Victoria E, Walton, Michael I, Eve, Paul D, Boxall, Katherine J, Antoni, Laurent, Caldwell, John J, Aherne, Wynne, Pearl, Laurence H, Oliver, Antony W, Collins, Ian and Garrett, Michelle D (2011) CCT241533 Is a Potent and Selective Inhibitor of CHK2 that Potentiates the Cytotoxicity of PARP Inhibitors. Cancer Research, 71 (2). pp. 463-472. ISSN 0008-5472 Mon, 06 Feb 2012 20:38:41 +0000 http://sro.sussex.ac.uk/id/eprint/27168/ http://sro.sussex.ac.uk/id/eprint/27168/ Nojima, Kuniharu, Hochegger, Helfrid, Saberi, Alihossein, Fukushima, Toru, Kikuchi, Koji, Yoshimura, Michio, Oreilli, Brian J, Bishop, Douglas K, Hirano, Seiki, Ohzeki, Mioko, Ishiai, Masamichi, Yamamoto, Kazuhiko, Takata, Minoru, Arakawa, Kiroshi, Buerstedde, Jean-Marie, Yamazoe, Mitsuyoshi, Kawamoto, Takuo, Araki, Kasumi, Takahashi, Jun A, Hashimoto, Nobuo, Takeda, Shunichi and Sonoda, Eiichiro (2005) Multiple repair pathways mediate tolerance to chemotherapeutic cross-linking agents in vertebrate cells. Cancer Research, 65 (24). pp. 11704-11711. ISSN 0008-5472 Mon, 06 Feb 2012 20:06:45 +0000 http://sro.sussex.ac.uk/id/eprint/24084/ http://sro.sussex.ac.uk/id/eprint/24084/ Tozer, Gillian M, Akerman, Simon, Cross, Neil A, Barber, Paul R, Bjorndahl, Meit A, Greco, Olga, Harris, Sheila, Hill, Sally A, Honness, Davina J, Ireson, Christopher R, Pettyjohn, Katie L, Prise, Vivien E, Reyes Aldasoro, Constantino C, Ruhrberg, Christina, Shima, David T and Kanthou, Chryso (2008) Blood vessel maturation and response to vascular-disrupting therapy in single vascular endothelial growth factor-A isoform-producing tumors. Cancer Research, 68 (7). pp. 2301-2311. ISSN 0008-5472 Mon, 06 Feb 2012 20:03:03 +0000 http://sro.sussex.ac.uk/id/eprint/23743/ http://sro.sussex.ac.uk/id/eprint/23743/ Girard, P M, Foray, N, Stumm, M, Waugh, A, Riballo, E, Maser, R S, Phillips, W P, Petrini, J, Arlett, C F and Jeggo, P A (2000) Radiosensitivity in Nijmegen Breakage Syndrome cells is attributable to a repair defect and not cell cycle checkpoint defects. Cancer Research, 60. 4881 - 4888. ISSN 0008-5472 Mon, 06 Feb 2012 19:50:57 +0000 http://sro.sussex.ac.uk/id/eprint/22509/ http://sro.sussex.ac.uk/id/eprint/22509/ Stiff, Thomas, O'Driscoll, Mark, Rief, N, Iwabuchi, K, Lobrich, M and Jeggo, Penny (2004) ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation. Cancer Research, 64 (7). pp. 2390-2396. ISSN 00085472 Mon, 06 Feb 2012 19:30:54 +0000 http://sro.sussex.ac.uk/id/eprint/20964/ http://sro.sussex.ac.uk/id/eprint/20964/ O'Driscoll, Mark (2004) Roles of DNA-PK, ATM and ATR in damage induced H2AX phosphorylation. Cancer Research, 67 (7). pp. 2390-2396. Mon, 06 Feb 2012 19:16:24 +0000 http://sro.sussex.ac.uk/id/eprint/19841/ http://sro.sussex.ac.uk/id/eprint/19841/ Slupianek, A, Poplawski, T, Jozwiakowski, Stanislaw, Cramer, K, Pytel, D, Stoczynska, E, Nowicki, MO, Blasiak, J and Skorski, T (2011) BCR/ABL stimulates WRN to promote survival and genomic instability. Cancer Research, 71 (3). pp. 842-851. ISSN 0008-5472 Mon, 06 Feb 2012 19:13:04 +0000 http://sro.sussex.ac.uk/id/eprint/19610/ http://sro.sussex.ac.uk/id/eprint/19610/ Jeffrey, Ian W, Bushell, Martin, Tilleray, Vivienne J, Morley, Simon and Clemens, Michael J (2002) Inhibition of protein synthesis in apoptosis: differential requirements by the tumor necrosis factor alpha family and a DNA-damaging agent for caspases and the double-stranded RNA-dependent protein kinase. Cancer Research, 62 (8). pp. 2272-2280. ISSN 0008-5472 Mon, 06 Feb 2012 18:35:26 +0000 http://sro.sussex.ac.uk/id/eprint/17276/ http://sro.sussex.ac.uk/id/eprint/17276/ Eccles, Suzanne A, Massey, Andy, Raynaud, Florence I, Sharp, Swee Y, Box, Gary, Valenti, Melanie, Patterson, Lisa, de Haven Brandon, Alexis, Gowan, Sharon, Boxall, Frances, Aherne, Wynne, Rowlands, Martin, Hayes, Angela, Martins, Vanessa, Urban, Frederique, Boxall, Kathy, Prodromou, Chrisostomos, Pearl, Laurence, James, Karen, Matthews, Thomas P, Cheung, Kwai-Ming, Kalusa, Andrew, Jones, Keith, McDonald, Edward, Barril, Xavier, Brough, Paul A, Cansfield, Julie E, Dymock, Brian, Drysdale, Martin J, Finch, Harry, Howes, Rob, Hubbard, Roderick E, Surgenor, Alan, Webb, Paul, Wood, Mike, Wright, Lisa and Workman, Paul (2008) NVP-AUY922: a novel heat shock protein 90 inhibitor active against xenograft tumor growth, angiogenesis, and metastasis. Cancer Research, 68 (8). pp. 2850-2860. ISSN 0008-5472 Fri, 26 Aug 2011 15:30:12 +0100 http://sro.sussex.ac.uk/id/eprint/7124/ http://sro.sussex.ac.uk/id/eprint/7124/ Mayer, M., Hunis, A., Oratz, R., Glennon, C., Spicer, P., Caplan, E. and Fallowfield, L.J. (2009) Importance of Providing Tailored Resources to Patients with Metastatic Breast Cancer: Results of the Global BRIDGE Survey. Cancer Research, 69 (24). 674S-674S. ISSN 0008-5472 http://sro.sussex.ac.uk/id/eprint/2118/ http://sro.sussex.ac.uk/id/eprint/2118/ Connell, Claire M, Wheatley, Sally P and McNeish, Iain A (2008) Nuclear survivin abrogates multiple cell cycle checkpoints and enhances viral oncolysis. Cancer Research, 68 (19). pp. 7923-7931. ISSN 1538-7445 (Electronic) http://sro.sussex.ac.uk/id/eprint/971/ http://sro.sussex.ac.uk/id/eprint/971/ Stiff, Thomas, O'Driscoll, Mark, Rief, N., Iwabuchi, K., Lobrich, M. and Jeggo, Penny (2004) ATM and DNA-PK function redundantly to phosphorylate H2AX following exposure to ioninsing radiation. Cancer Research, 64 (7). pp. 2390-2396. ISSN 0008-5472 http://sro.sussex.ac.uk/id/eprint/979/ http://sro.sussex.ac.uk/id/eprint/979/ Kuhne, M., Riballo, E., Rief, N., Rothkamm, K., Jeggo, Penny and Lobrich, M. (2004) A double-strand break repair defect in ATM-deficient cells contributes to radiosensitivity. Cancer Research, 64 (2). pp. 500-508. ISSN 0008-5472 http://sro.sussex.ac.uk/id/eprint/963/ http://sro.sussex.ac.uk/id/eprint/963/ Bavoux, C., Leopoldino, A. M., Bergoglio, V., J, O. Wang, Ogi, T., Bieth, A., Judde, J. G., Pena, S. D., Poupon, M. F., Helleday, T., Tagawa, M., Machado, C., Hoffmann, J. S. and Cazaux, C. (2005) Up-regulation of the error-prone DNA polymerase {kappa} promotes pleiotropic genetic alterations and tumorigenesis. Cancer Research, 65 (1). pp. 325-30. ISSN 0008-5472 http://sro.sussex.ac.uk/id/eprint/965/ http://sro.sussex.ac.uk/id/eprint/965/ Albertella, Mark R., Green, Catherine M., Lehmann, Alan R. and O'Connor, Mark J. (2005) A Role for Polymerase η in the Cellular Tolerance to Cisplatin-Induced Damage. Cancer Research, 65 (21). pp. 9799-806. ISSN 0008-5472