Sussex Research Online: No conditions. Results ordered -Date Deposited. http://sro.sussex.ac.uk/ http://sro.sussex.ac.uk/images/sitelogo.png Sussex Research Online: No conditions. Results ordered -Date Deposited. http://sro.sussex.ac.uk/ Mon, 20 Nov 2023 21:41:14 +0000 Mon, 20 Nov 2023 21:41:14 +0000 en Thu, 12 Jan 2023 10:21:55 +0000 Fibroblast-kinome silencing to identifies putative mediator of Triple-negative breast cancer (TNBC) invasion http://sro.sussex.ac.uk/id/eprint/110103/ http://sro.sussex.ac.uk/id/eprint/110103/ Gagliano, Teresa, Vella, Viviana, Bienkowska, Kamila, Ditsiou, Angeliki and Giamas, Georgios (2018) Fibroblast-kinome silencing to identifies putative mediator of Triple-negative breast cancer (TNBC) invasion. In: 20th European Congress of Endocrinology, 19th May - 22nd May 2018, Barcelona, Spain. Tue, 21 Jun 2022 11:14:00 +0100 Erratum to: RPAP3 provides a flexible scaffold for coupling HSP90 to the human R2TP co-chaperone complex http://sro.sussex.ac.uk/id/eprint/106478/ http://sro.sussex.ac.uk/id/eprint/106478/ Martino, Fabrizio, Pal, Mohinder, Muñoz-Hernández, Hugo, Rodríguez, Carlos F, Núñez-Ramírez, Rafael, Gil-Carton, David, Degliesposti, Gianluca, Skehel, J Mark, Roe, S Mark, Prodromou, Chrisostomos, Pearl, Laurence H and Llorca, Oscar (2018) Erratum to: RPAP3 provides a flexible scaffold for coupling HSP90 to the human R2TP co-chaperone complex. Nature Communications, 9. p. 3063. ISSN 2041-1723 Tue, 21 Jun 2022 10:51:40 +0100 Corrigendum: The integrity and organization of the human AIPL1 functional domains is critical for its role as a HSP90-dependent co-chaperone for rod PDE6 http://sro.sussex.ac.uk/id/eprint/106476/ http://sro.sussex.ac.uk/id/eprint/106476/ Sacristan-Reviriego, Almudena, Bellingham, James, Prodromou, Chrisostomos, Boehm, Annika N, Aichem, Annette, Kumaran, Neruban, Bainbridge, James, Michaelides, Michel and van der Spuy, Jacqueline (2018) Corrigendum: The integrity and organization of the human AIPL1 functional domains is critical for its role as a HSP90-dependent co-chaperone for rod PDE6. Human Molecular Genetics, 27 (7). p. 1309. ISSN 0964-6906 Tue, 21 Jun 2022 10:46:37 +0100 Targeting treatment resistance in breast cancer subtypes via LMTK3 inhibition http://sro.sussex.ac.uk/id/eprint/106475/ http://sro.sussex.ac.uk/id/eprint/106475/ Ditsiou, Angeliki, Gagliano, Teresa, Prodromou, Chrisostomos, Gascon, Jose, Mumford, Sophie, Grand, Darren Le and Giamas, Georgios (2018) Targeting treatment resistance in breast cancer subtypes via LMTK3 inhibition. In: 20th European Congress of Endocrinology, 19-22 May 2018, Barcelona, Spain. Mon, 01 Nov 2021 08:45:01 +0000 Sterically encumbered mixed sandwich compounds of uranium(III): synthesis and reactivity with small molecules http://sro.sussex.ac.uk/id/eprint/102577/ http://sro.sussex.ac.uk/id/eprint/102577/ Kahan, Rachel J, Farnaby, Joy H, Tsoureas, Nikolaos, Cloke, F Geoffrey N, Hitchcock, Peter B, Coles, Martyn P, Roe, S Mark and Wilson, Claire (2018) Sterically encumbered mixed sandwich compounds of uranium(III): synthesis and reactivity with small molecules. Journal of Organometallic Chemistry, 857. pp. 110-122. ISSN 0022-328X Thu, 07 Nov 2019 09:48:11 +0000 Structural insights into the inhibition of Zika virus NS2B-NS3 protease by a small-molecule inhibitor http://sro.sussex.ac.uk/id/eprint/87884/ http://sro.sussex.ac.uk/id/eprint/87884/ Li, Yan, Zhang, Zhenzhen, Phoo, Wint Wint, Loh, Ying Ru, Li, Rong, Yang, Hai Yan, Jansson, Anna E, Hill, Jeffrey, Keller, Thomas H, Nacro, Kassoum, Luo, Dahai and Kang, CongBao (2018) Structural insights into the inhibition of Zika virus NS2B-NS3 protease by a small-molecule inhibitor. Structure, 26 (4). pp. 555-564. ISSN 0969-2126 Thu, 07 Nov 2019 09:09:21 +0000 Targeting cancer addiction for SALL4 by shifting its transcriptome with a pharmacologic peptide http://sro.sussex.ac.uk/id/eprint/87873/ http://sro.sussex.ac.uk/id/eprint/87873/ Hui Liu, Bee, Jobichen, Chacko, Chia, C S Brian, Chan, Tim Hon Man, Tang, Jing Ping, Chung, Theodora X Y, Li, Jia, Poulsen, Anders, Hung, Alvin W, Koh-Stenta, Xiaoying, Tan, Yaw Sing, Verma, Chandra S, Tan, Hong Kee, Wu, Chan-Shuo, Li, Feng, Hill, Jeffrey and others, (2018) Targeting cancer addiction for SALL4 by shifting its transcriptome with a pharmacologic peptide. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 115 (30). pp. 7119-7128. ISSN 1091-6490 Mon, 15 Jul 2019 08:27:36 +0100 Elimination of ribosome inactivating factors improves the efficiency of and cell-free translation systems http://sro.sussex.ac.uk/id/eprint/84898/ http://sro.sussex.ac.uk/id/eprint/84898/ Brodiazhenko, Tetiana, Johansson, Marcus J O, Takada, Hiraku, Nissan, Tracy, Hauryliuk, Vasili and Murina, Victoriia (2018) Elimination of ribosome inactivating factors improves the efficiency of and cell-free translation systems. Frontiers in Microbiology, 9 (3041). pp. 1-9. ISSN 1664-302X Wed, 23 Jan 2019 10:57:37 +0000 Co‐crystallization of human inositol monophosphatase with the lithium mimetic L‐690,330 http://sro.sussex.ac.uk/id/eprint/81427/ http://sro.sussex.ac.uk/id/eprint/81427/ Kraft, L, Roe, M, Gill, R and Atack, J R (2018) Co‐crystallization of human inositol monophosphatase with the lithium mimetic L‐690,330. Acta Crystallographica Section D: Structural Biology, 74. pp. 973-978. ISSN 0907-4449 Thu, 10 Jan 2019 12:08:04 +0000 In vivo bioassay to test the pathogenicity of missense human AIP variants http://sro.sussex.ac.uk/id/eprint/81184/ http://sro.sussex.ac.uk/id/eprint/81184/ Aflorei, Elena Daniela, Klapholz, Benjamin, Chen, Chenghao, Radian, Serban, Dragu, Anca Neluta, Moderau, Nina, Prodromou, Chrisostomos, Ribeiro, Paulo S, Stanewsky, Ralf and Korbonits, Marta (2018) In vivo bioassay to test the pathogenicity of missense human AIP variants. Journal of Medical Genetics, 55. pp. 522-529. ISSN 0022-2593 Fri, 14 Dec 2018 15:27:57 +0000 Advances on the structure of the R2TP/Prefoldin-like complex http://sro.sussex.ac.uk/id/eprint/80799/ http://sro.sussex.ac.uk/id/eprint/80799/ Muñoz-Hernández, Hugo, Pal, Mohinder, Rodríguez, Carlos F, Prodromou, Chrisostomos, Pearl, Laurence H and Lllorca, Oscar (2018) Advances on the structure of the R2TP/Prefoldin-like complex. In: Djouder, Nabil (ed.) PrefoldinsL the new chaperones. Advances in Experimental Medicine and Biology, 1106 . Springer, Cham, pp. 73-83. ISBN 9783030007362 Thu, 06 Dec 2018 11:26:56 +0000 Two interlinked bistable switches govern mitotic control in mammalian cells http://sro.sussex.ac.uk/id/eprint/80629/ http://sro.sussex.ac.uk/id/eprint/80629/ Rata, Scott, Suarez Peredo Rodriguez, Maria F, Joseph, Stephy, Peter, Nisha, Echegaray Iturra, Fabio, Yang, Fengwei, Madzvamuse, Anotida, Ruppert, Jan G, Samejima, Kumiko, Platani, Melpomeni, Alvarez-Fernandez, Monica, Malumbres, Marcos, Earnshaw, William C, Novak, Bela and Hochegger, Helfrid (2018) Two interlinked bistable switches govern mitotic control in mammalian cells. Current Biology, 28 (23). 3824-3832.e6. ISSN 0960-9822 Fri, 30 Nov 2018 15:44:33 +0000 The biological role and mechanism of action of rbpA and carD in Streptomyces coelicolor A3 (2) and Mycobacterium tuberculosis http://sro.sussex.ac.uk/id/eprint/80557/ http://sro.sussex.ac.uk/id/eprint/80557/ Jagatia, Heena (2018) The biological role and mechanism of action of rbpA and carD in Streptomyces coelicolor A3 (2) and Mycobacterium tuberculosis. Doctoral thesis (PhD), University of Sussex. Mon, 26 Nov 2018 12:23:43 +0000 Cytocidal activity of Cry41Aa, an anticancer toxin from Bacillus thuringiensis http://sro.sussex.ac.uk/id/eprint/80446/ http://sro.sussex.ac.uk/id/eprint/80446/ Souissi, Wided (2018) Cytocidal activity of Cry41Aa, an anticancer toxin from Bacillus thuringiensis. Doctoral thesis (PhD), University of Sussex. Fri, 23 Nov 2018 17:14:33 +0000 Molecular evolution of prolactin in Chiroptera: accelerated evolution and a large insertion in vespertilionid bats http://sro.sussex.ac.uk/id/eprint/80384/ http://sro.sussex.ac.uk/id/eprint/80384/ Wallis, Michael (2018) Molecular evolution of prolactin in Chiroptera: accelerated evolution and a large insertion in vespertilionid bats. General and Comparative Endocrinology, 269. pp. 102-111. ISSN 0016-6480 Tue, 20 Nov 2018 10:03:29 +0000 Detecting intracellular thiol redox state in leukaemia and heterogeneous immune cell populations: an optimised protocol for digital flow cytometers http://sro.sussex.ac.uk/id/eprint/79541/ http://sro.sussex.ac.uk/id/eprint/79541/ Wadley, Alex J, Morgan, Rhys, Heesom, Kate J, Hole, Paul S and Coles, Steven J (2018) Detecting intracellular thiol redox state in leukaemia and heterogeneous immune cell populations: an optimised protocol for digital flow cytometers. MethodsX, 5. pp. 1473-1483. ISSN 2215-0161 Fri, 09 Nov 2018 11:04:39 +0000 Methods for structural analysis of amyloid fibrils in misfolding diseases http://sro.sussex.ac.uk/id/eprint/80066/ http://sro.sussex.ac.uk/id/eprint/80066/ Vadukul, Devekee M, Al-Hilaly, Youssra K and Serpell, Louise C (2018) Methods for structural analysis of amyloid fibrils in misfolding diseases. In: Gomes, Cláudio M (ed.) Protein misfolding diseases. Humana Press, New York, NY, pp. 109-122. ISBN 9781493988198 Thu, 01 Nov 2018 12:33:43 +0000 Disruption of CTCF-YY1–dependent looping of the human papillomavirus genome activates differentiation-induced viral oncogene transcription http://sro.sussex.ac.uk/id/eprint/79822/ http://sro.sussex.ac.uk/id/eprint/79822/ Pentland, Ieisha, Campos-León, Karen, Cotic, Marius, Davies, Kelli-Jo, Wood, C David, Groves, Ian J, Burley, Megan, Coleman, Nicholas, Stockton, Joanne D, Noyvert, Boris, Beggs, Andrew, West, Michelle J, Roberts, Sally and Parish, Joanna L (2018) Disruption of CTCF-YY1–dependent looping of the human papillomavirus genome activates differentiation-induced viral oncogene transcription. PLoS Biology, 16 (10). e2005752 1-28. ISSN 1544-9173 Tue, 16 Oct 2018 16:36:16 +0100 Novel pharmacist-led intervention secures the minimally important difference (MID) in Asthma Control Test (ACT) score: better outcomes for patients and the healthcare provider http://sro.sussex.ac.uk/id/eprint/79513/ http://sro.sussex.ac.uk/id/eprint/79513/ Tinelli, Michela, John, White and Manfrin, Andrea (2018) Novel pharmacist-led intervention secures the minimally important difference (MID) in Asthma Control Test (ACT) score: better outcomes for patients and the healthcare provider. BMJ Open Respiratory Research, 2018 (5). e000322 1-9. ISSN 2052-4439, Fri, 12 Oct 2018 13:56:38 +0100 The X-ray structure of human calbindin-D28K: an improved model http://sro.sussex.ac.uk/id/eprint/79457/ http://sro.sussex.ac.uk/id/eprint/79457/ Noble, James William, Almalki, Rehab, Roe, Mark, Duman, Ramona, Wagner, Armin and Atack, John (2018) The X-ray structure of human calbindin-D28K: an improved model. Acta Crystallographica Section D: Structural Biology, 74 (10). pp. 1008-1014. ISSN 2059-7983 Thu, 11 Oct 2018 13:29:57 +0100 The human gut colonizer blastocystis respires using complex II and alternative oxidase to buffer transient oxygen fluctuations in the gut http://sro.sussex.ac.uk/id/eprint/79336/ http://sro.sussex.ac.uk/id/eprint/79336/ Tsaousis, Anastasios D, Hamblin, Karleigh A, Elliott, Kate, Young, Luke, Rosell Hidalgo, Alicia, Gourlay, Campbell W, Moore, Anthony and van der Giezen, Mark (2018) The human gut colonizer blastocystis respires using complex II and alternative oxidase to buffer transient oxygen fluctuations in the gut. Frontiers in Cellular and Infection Microbiology, 8 (371). pp. 1-11. ISSN 2235-2988 Tue, 09 Oct 2018 14:38:15 +0100 Selective cytotoxicity of dihydroorotate dehydrogenase inhibitors to human cancer cells under hypoxia and nutrient-deprived conditions http://sro.sussex.ac.uk/id/eprint/79297/ http://sro.sussex.ac.uk/id/eprint/79297/ Miyazaki, Yuki, Inaoka, Daniel, Shiba, Tomoo, Saimoto, Hiroyuki, Sakura, Takaya, Amalia, Eri, Kido, Yasutoshi, Sakai, Chika, Nakamura, Mari, Moore, Anthony, Harada, Shigeharu and Kita, Kiyoshi (2018) Selective cytotoxicity of dihydroorotate dehydrogenase inhibitors to human cancer cells under hypoxia and nutrient-deprived conditions. Frontiers in Pharmacology, 9 (997). pp. 1-13. ISSN 1663-9812 Tue, 09 Oct 2018 13:51:37 +0100 A single blind, multicenter, randomized controlled trial to evaluate the effectiveness and cost of a novel nutraceutical (LopiGLIK®) lowering cardiovascular disease risk http://sro.sussex.ac.uk/id/eprint/79286/ http://sro.sussex.ac.uk/id/eprint/79286/ Manfrin, Andrea, Trimarco, Valentina, Manzi, Maria Virginia, Rozza, Francesco and Izzo, Raffaele (2018) A single blind, multicenter, randomized controlled trial to evaluate the effectiveness and cost of a novel nutraceutical (LopiGLIK®) lowering cardiovascular disease risk. ClinicoEconomics and Outcomes Research, 10. pp. 601-609. ISSN 1178-6981 Thu, 27 Sep 2018 10:26:57 +0100 Synthesis of novel heteroleptic delocalised cationic pyrazole gold complexes as potent HepG2 cytotoxic agents http://sro.sussex.ac.uk/id/eprint/79050/ http://sro.sussex.ac.uk/id/eprint/79050/ Afolabi, Fatai, Souissi, Wided, Rivière, Guillaume, Lemaitre, Clement, Roe, Mark, Crickmore, Neil and Viseux, Eddy (2018) Synthesis of novel heteroleptic delocalised cationic pyrazole gold complexes as potent HepG2 cytotoxic agents. Dalton Transactions, 47 (43). pp. 15338-15343. ISSN 1477-9226 Fri, 14 Sep 2018 14:20:22 +0100 Consistency and replicability of a pharmacist-led intervention for asthma patients: Italian Medicines Use Review (I-MUR) http://sro.sussex.ac.uk/id/eprint/78774/ http://sro.sussex.ac.uk/id/eprint/78774/ Manfrin, Andrea and Krska, Janet (2018) Consistency and replicability of a pharmacist-led intervention for asthma patients: Italian Medicines Use Review (I-MUR). Primary Health Care Research & Development, 20. pp. 1-8. ISSN 1463-4236 Thu, 13 Sep 2018 08:36:50 +0100 [Letter to editor] Shedding of bevacizumab in tumour cells derived extracellular vesicles as a new therapeutic escape mechanism in glioblastoma http://sro.sussex.ac.uk/id/eprint/78685/ http://sro.sussex.ac.uk/id/eprint/78685/ Simon, Thomas, Pinioti, Sotiria, Schellenberger, Pascale, Rajeeve, Vinothini, Wendler, Franz, Cutillas, Pedro R, King, Alice, Stebbing, Justin and Giamas, Georgios (2018) [Letter to editor] Shedding of bevacizumab in tumour cells derived extracellular vesicles as a new therapeutic escape mechanism in glioblastoma. Molecular Cancer, 17 (132). pp. 1-7. ISSN 1476-4598 Fri, 31 Aug 2018 08:48:36 +0100 Cysteine-independent inhibition of alzheimer's disease-like paired helical filament assembly by leuco-methylthioninium (LMT) http://sro.sussex.ac.uk/id/eprint/78404/ http://sro.sussex.ac.uk/id/eprint/78404/ Al-Hilaly, Youssra K, Pollack, Saskia J, Rickard, Janet E, Simpson, Michael, Raulin, Ana-C, Baddeley, Thomas, Schellenberger, Pascale, Storey, John M D, Harrington, Charles R, Wischik, Claude M and Serpell, Louise C (2018) Cysteine-independent inhibition of alzheimer's disease-like paired helical filament assembly by leuco-methylthioninium (LMT). Journal of Molecular Biology, 430 (21). pp. 4119-4131. ISSN 0022-2836 Fri, 31 Aug 2018 08:35:00 +0100 Identifying the coiled-coil triple helix structure of β-peptide nanofibers at atomic resolution http://sro.sussex.ac.uk/id/eprint/78403/ http://sro.sussex.ac.uk/id/eprint/78403/ Christofferson, Andrew J, Al-Garawi, Zahraa S, Todorova, Nevena, Turner, Jack, Del Borgo, Mark Pasqualino, Serpell, Louise C, Aguilar, Marie-Isabel and Yarovsky, Irene (2018) Identifying the coiled-coil triple helix structure of β-peptide nanofibers at atomic resolution. ACS Nano, 12 (9). pp. 9101-9109. ISSN 1936-0851 Fri, 24 Aug 2018 14:38:20 +0100 Probing the anticancer action of novel ferrocene analogues of MNK inhibitors http://sro.sussex.ac.uk/id/eprint/78281/ http://sro.sussex.ac.uk/id/eprint/78281/ Sansook, Supojjanee, Lineham, Ella, Hassell-Hart, Storm, Tizzard, Graham J, Coles, Simon J, Spencer, John and Morley, Simon J (2018) Probing the anticancer action of novel ferrocene analogues of MNK inhibitors. Molecules, 23 (2126). pp. 1-13. ISSN 1420-3049 Mon, 13 Aug 2018 13:51:37 +0100 The involvement of Aβ42 and tau in nucleolar and protein synthesis machinery dysfunction http://sro.sussex.ac.uk/id/eprint/77778/ http://sro.sussex.ac.uk/id/eprint/77778/ Maina, Mahmoud B, Bailey, Laura J, Doherty, Aidan J and Serpell, Louise C (2018) The involvement of Aβ42 and tau in nucleolar and protein synthesis machinery dysfunction. Frontiers in Cellular Neuroscience, 12 (220). pp. 1-13. ISSN 1662-5102 Mon, 13 Aug 2018 13:42:37 +0100 The involvement of tau in nucleolar transcription and the stress response http://sro.sussex.ac.uk/id/eprint/77777/ http://sro.sussex.ac.uk/id/eprint/77777/ Maina, Mahmoud B, Bailey, Laura J, Wagih, Sherin, Biasetti, Luca, Pollack, Saskia J, Quinn, James P, Thorpe, Julian R, Doherty, Aidan J and Serpell, Louise C (2018) The involvement of tau in nucleolar transcription and the stress response. Acta Neuropathologica Communications, 6 (70). pp. 1-13. ISSN 2051-5960 Fri, 10 Aug 2018 16:14:53 +0100 IRF4 in multiple myeloma—biology, disease and therapeutic target http://sro.sussex.ac.uk/id/eprint/77753/ http://sro.sussex.ac.uk/id/eprint/77753/ Agnarelli, Alessandro, Chevassut, Timothy and Mancini, Erika (2018) IRF4 in multiple myeloma—biology, disease and therapeutic target. Leukemia Research, 72. pp. 52-58. ISSN 0145-2126 Tue, 07 Aug 2018 15:36:01 +0100 Mapping genetic variations to three- dimensional protein structures to enhance variant interpretation: a proposed framework http://sro.sussex.ac.uk/id/eprint/77591/ http://sro.sussex.ac.uk/id/eprint/77591/ Glusman, Gustavo, Rose, Peter W, Prlić, Andrea, Dougherty, Jennifer, Duarte, José M, Hoffmann, Andrew S, Barton, Geoffery J, Bendixen, Emøke, Bergquist, Timothy, Bock, Christian, Brunk, Elizabeth, Buljan, Marija, Burley, Stephen K, Cai, Binguang, Carter, Hannah, Gao, JiangJong, Godzik, Adam, Heuer, Michael, Hicks, Michael, Hrabe, Thomas, Karchin, Rachel, Kohler Leman, Julia, Lane, Lydie, Masica, David L, Mooney, Sean D, Moult, John, Omenn, Gilbert S, Pearl, Frances, Pejavar, Vikas, Reynolds, Sheila M, Rokem, Ariel, Schwede, Torsten, Song, Sicheng, Tilger, Hagen, Valasatava, Yana, Zhang, Yang and Deutsch, Eric W (2018) Mapping genetic variations to three- dimensional protein structures to enhance variant interpretation: a proposed framework. Genome Medicine, 9 (113). pp. 1-10. ISSN 1756-994X Wed, 01 Aug 2018 14:30:06 +0100 Cry78Aa, a novel Bacillus thuringiensis insecticidal protein with activity against Laodelphax striatellus and Nilaparvata lugens http://sro.sussex.ac.uk/id/eprint/77461/ http://sro.sussex.ac.uk/id/eprint/77461/ Wang, Yinglong, Liu, Yonglei, Zhang, Jie, Crickmore, Neil, Song, Fuping, Gao, Jiguo and Shu, Changlong (2018) Cry78Aa, a novel Bacillus thuringiensis insecticidal protein with activity against Laodelphax striatellus and Nilaparvata lugens. Journal of invertebrate pathology, 158. pp. 1-5. ISSN 1096-0805 Thu, 26 Jul 2018 08:26:14 +0100 Enhancer control of MicroRNA miR-155 expression in EpsteinBarr virus-infected B cells http://sro.sussex.ac.uk/id/eprint/77382/ http://sro.sussex.ac.uk/id/eprint/77382/ Wood, C David, Carvell, Thomas, Gunnell, Andrea, Ojeniyi, Opeoluwa O, Osborne, Cameron and West, Michelle J (2018) Enhancer control of MicroRNA miR-155 expression in EpsteinBarr virus-infected B cells. Journal of Virology, 92 (19). e000716-18 1 1. ISSN 0022-538X Mon, 23 Jul 2018 13:13:12 +0100 Thermodynamic and structural analysis of the interactions between Epstein-Barr virus transcription factors and the host targeting factor RBP-Jkappa http://sro.sussex.ac.uk/id/eprint/77332/ http://sro.sussex.ac.uk/id/eprint/77332/ Simmons, Robert (2018) Thermodynamic and structural analysis of the interactions between Epstein-Barr virus transcription factors and the host targeting factor RBP-Jkappa. Doctoral thesis (PhD), University of Sussex. Fri, 22 Jun 2018 10:10:01 +0100 Development of a high-throughput ex-vivo burn wound model using porcine skin, and its application to evaluate new approaches to control wound infection http://sro.sussex.ac.uk/id/eprint/76666/ http://sro.sussex.ac.uk/id/eprint/76666/ Alves, Diana R, Booth, Simon P, Scavone, Paola, Schellenberger, Pascale, Salvage, Jonathan, Dedi, Cinzia, Thet, Naing-Tun, Jenkins, A Toby A, Waters, Ryan, Ng, Keng W, Overall, Andrew D J, Metcalfe, Anthony D, Nzakizwanayo, Jonathan and Jones, Brian V (2018) Development of a high-throughput ex-vivo burn wound model using porcine skin, and its application to evaluate new approaches to control wound infection. Frontiers in Cellular and Infection Microbiology, 8. ISSN 2235-2988 Wed, 20 Jun 2018 16:13:08 +0100 Exploring interactions between Epstein-Barr virus transcription factor Zta and the human genome http://sro.sussex.ac.uk/id/eprint/76667/ http://sro.sussex.ac.uk/id/eprint/76667/ Naranjo Perez Fernandez, Ijiel Barak (2018) Exploring interactions between Epstein-Barr virus transcription factor Zta and the human genome. Doctoral thesis (PhD), University of Sussex. Fri, 15 Jun 2018 08:44:25 +0100 Visceral adipose tissue immune homeostasis is regulated by the crosstalk between adipocytes and dendritic cell subsets http://sro.sussex.ac.uk/id/eprint/76516/ http://sro.sussex.ac.uk/id/eprint/76516/ Macdougall, Claire E, Wood, Elizabeth G, Loschko, Jakob, Scagliotti, Valeria, Cassidy, Féaron C, Robinson, Mark E, Feldhahn, Niklas, Castellano, Leandro, Voisin, Mathieu-Benoit, Marelli-Berg, Federica, Gaston-Massuet, Carles, Charalambous, Marika and Longhi, M Paula (2018) Visceral adipose tissue immune homeostasis is regulated by the crosstalk between adipocytes and dendritic cell subsets. Cell Metabolism, 27 (3). 588-601.e4. ISSN 1550-4131 Fri, 15 Jun 2018 08:39:07 +0100 Novel tumour suppressive protein encoded by circular RNA, circ-SHPRH, in glioblastomas http://sro.sussex.ac.uk/id/eprint/76515/ http://sro.sussex.ac.uk/id/eprint/76515/ Begum, S, Yiu, A, Stebbing, J and Castellano, L (2018) Novel tumour suppressive protein encoded by circular RNA, circ-SHPRH, in glioblastomas. Oncogene, 37. pp. 4055-4057. ISSN 1476-5594 Fri, 15 Jun 2018 08:17:20 +0100 Glypican-1 is enriched in circulating-exosomes in pancreatic cancer and correlates with tumor burden http://sro.sussex.ac.uk/id/eprint/76513/ http://sro.sussex.ac.uk/id/eprint/76513/ Frampton, Adam E, Prado, Mireia Mato, López-Jiménez, Elena, Fajardo-Puerta, Ana Belen, Jawad, Zaynab A R, Lawton, Phillip, Giovannetti, Elisa, Habib, Nagy A, Castellano, Leandro, Stebbing, Justin, Krell, Jonathan and Jiao, Long R (2018) Glypican-1 is enriched in circulating-exosomes in pancreatic cancer and correlates with tumor burden. Oncotarget, 9 (27). pp. 19006-19013. ISSN 1949-2553 Thu, 14 Jun 2018 13:22:44 +0100 Chemico-calorimetric analysis of amorphous granules manufactured via continuous granulation process http://sro.sussex.ac.uk/id/eprint/76486/ http://sro.sussex.ac.uk/id/eprint/76486/ Majumder, Mridul, Rajabnezhad, Saeid, Nokhodchi, Ali and Maniruzzaman, Mohammed (2018) Chemico-calorimetric analysis of amorphous granules manufactured via continuous granulation process. Drug Delivery and Translational Research, 8 (6). pp. 1658-1669. ISSN 2190-393X Thu, 14 Jun 2018 13:13:40 +0100 Dihydropyridines allosterically modulate Hsp90 providing a novel mechanism for heat shock protein co-induction and neuroprotection http://sro.sussex.ac.uk/id/eprint/76485/ http://sro.sussex.ac.uk/id/eprint/76485/ Roe, Mark, Wahab, Ben, Torok, Zsolt, Horvath, Ibolya, Vigh, Laszlo and Prodromou, Chrisostomos (2018) Dihydropyridines allosterically modulate Hsp90 providing a novel mechanism for heat shock protein co-induction and neuroprotection. Frontiers in Molecular Biosciences, 5 (51). pp. 1-14. ISSN 2296-889X Wed, 13 Jun 2018 11:40:21 +0100 TGF-ß induces miR-100 and miR-125b but blocks let-7a through LIN28B controlling PDAC progression. http://sro.sussex.ac.uk/id/eprint/76468/ http://sro.sussex.ac.uk/id/eprint/76468/ Ottaviani, Silvia, Stebbing, Justin, Frampton, Adam E, Zagorac, Sladjana, Krell, Jonathan, de Giorgio, Alexander, Trabulo, Sara M, Nguyen, Van T M, Magnani, Luca, Feng, Hugang, Giovannetti, Elisa, Funel, Nicola, Gress, Thomas, Jiao, Long, Lombardo, Ylenia, Lemoine, Nicholas R, Heeschen, Christopher and Castellano, Leandro (2018) TGF-ß induces miR-100 and miR-125b but blocks let-7a through LIN28B controlling PDAC progression. Nature Communications, 9 (1845). pp. 1-18. ISSN 2041-1723 Tue, 05 Jun 2018 08:33:10 +0100 Activity of acetyltransferase toxins involved in Salmonella persister formation during macrophage infection http://sro.sussex.ac.uk/id/eprint/76325/ http://sro.sussex.ac.uk/id/eprint/76325/ Rycroft, Julian A, Gollan, Bridget, Grabe, Grzegorz J, Hall, Alexander, Cheverton, Angela M, Larrouy-Maumus, Gerald, Hare, Stephen A and Helaine, Sophie (2018) Activity of acetyltransferase toxins involved in Salmonella persister formation during macrophage infection. Nature Communications, 9 (1993). pp. 1-11. ISSN 2041-1723 Tue, 29 May 2018 10:46:12 +0100 [Abstract] Public preferences for wording of dosage instructions on dispensed medicine labels http://sro.sussex.ac.uk/id/eprint/76098/ http://sro.sussex.ac.uk/id/eprint/76098/ Manfrin, A, Rodgers, R M and Krska, J (2018) [Abstract] Public preferences for wording of dosage instructions on dispensed medicine labels. Prescribing and Research in Medicines Management (UK & Ireland) Annual Conference 2018, London, 26th January 2018. Published in: Pharmacoepidemiology and Drug Safety. 27 (S1) 11-11. Wiley ISSN 1053-8569 Thu, 10 May 2018 15:22:25 +0100 Targeting LGR5 in colorectal cancer: therapeutic gold or too plastic? http://sro.sussex.ac.uk/id/eprint/75757/ http://sro.sussex.ac.uk/id/eprint/75757/ Morgan, R G, Mortensson, E and Williams, A C (2018) Targeting LGR5 in colorectal cancer: therapeutic gold or too plastic? British Journal of Cancer, 118. pp. 1410-1418. ISSN 0007-0920 Thu, 10 May 2018 15:11:40 +0100 Optimized delivery of siRNA into 3D tumor spheroid cultures in situ http://sro.sussex.ac.uk/id/eprint/75758/ http://sro.sussex.ac.uk/id/eprint/75758/ Morgan, R G, Chambers, A C, Legge, D N, Coles, S J, Greenhough, A and Williams, A C (2018) Optimized delivery of siRNA into 3D tumor spheroid cultures in situ. Scientific Reports, 8 (7592). pp. 1-10. ISSN 2045-2322 Thu, 10 May 2018 14:43:44 +0100 Preliminary evidence of reductive stress in human cytotoxic T-cells following exercise http://sro.sussex.ac.uk/id/eprint/75697/ http://sro.sussex.ac.uk/id/eprint/75697/ Wadley, Alex J, Holliday, Adrian, Morgan, Rhys G, Heesom, Kate J, Aldred, Sarah, Peters, Derek M, Bueno, Allain A and Coles, Steven J (2018) Preliminary evidence of reductive stress in human cytotoxic T-cells following exercise. Journal of Applied Physiology, 125 (2). pp. 586-595. ISSN 8750-7587 Thu, 10 May 2018 14:24:03 +0100 LGR5 expression is regulated by EGF in early colorectal adenomas and governs EGFR inhibitor sensitivity. http://sro.sussex.ac.uk/id/eprint/75696/ http://sro.sussex.ac.uk/id/eprint/75696/ Morgan, R G, Mortensson, E, Legge, D N, Gupta, B, Collard, T J, Greenhough, A and Williams, A C (2018) LGR5 expression is regulated by EGF in early colorectal adenomas and governs EGFR inhibitor sensitivity. British Journal of Cancer, 118 (4). pp. 558-565. ISSN 1532-1827 Thu, 03 May 2018 15:10:19 +0100 Formation of functional, non-amyloidogenic fibres by recombinant Bacillus subtilis TasA http://sro.sussex.ac.uk/id/eprint/75601/ http://sro.sussex.ac.uk/id/eprint/75601/ Erskine, Elliot, Morris, Ryan J, Schor, Marieke, Earl, Chris, Gillespie, Rachel M C, Bromley, Keith, Sukhodub, Tetyana, Clark, Lauren, Fyfe, Paul, Serpell, Louise C, Stanley-Wall, Nicola R and MacPhee, Cait E (2018) Formation of functional, non-amyloidogenic fibres by recombinant Bacillus subtilis TasA. Molecular Microbiology, 110 (6). pp. 897-913. ISSN 0950-382X Thu, 26 Apr 2018 09:15:53 +0100 Identification and characterisation of a novel inhibitor of serine racemase through a fragment-based drug discovery strategy http://sro.sussex.ac.uk/id/eprint/75370/ http://sro.sussex.ac.uk/id/eprint/75370/ Koulouris, Chloe Rose (2018) Identification and characterisation of a novel inhibitor of serine racemase through a fragment-based drug discovery strategy. Doctoral thesis (PhD), University of Sussex. Mon, 16 Apr 2018 14:43:08 +0100 RPAP3 provides a flexible scaffold for coupling HSP90 to the human R2TP co-chaperone complex http://sro.sussex.ac.uk/id/eprint/75133/ http://sro.sussex.ac.uk/id/eprint/75133/ Martino, Fabrizio, Pal, Mohinder, Muñoz-Hernández, Hugo, Rodríguez, Carlos F, Núñez-Ramírez, Rafael, Gil-Carton, David, Degliesposti, Gianluca, Skehel, J Mark, Roe, S Mark, Prodromou, Chrisostomos, Pearl, Laurence H and Llorca, Oscar (2018) RPAP3 provides a flexible scaffold for coupling HSP90 to the human R2TP co-chaperone complex. Nature Communications, 9 (1). ISSN 2041-1723 Fri, 13 Apr 2018 14:43:10 +0100 Structure-based drug discovery approaches to identify modulators of the Nrf2 pathway and glutamate receptors AMPA GluA2 and Kainate GluK1 and GluK2 http://sro.sussex.ac.uk/id/eprint/75046/ http://sro.sussex.ac.uk/id/eprint/75046/ Carreno Velazquez, Thalia Lizbeth (2018) Structure-based drug discovery approaches to identify modulators of the Nrf2 pathway and glutamate receptors AMPA GluA2 and Kainate GluK1 and GluK2. Doctoral thesis (PhD), University of Sussex. Tue, 10 Apr 2018 15:09:40 +0100 Mechanism of activation of the BNLF2a immune evasion gene of Epstein-Barr virus by Zta http://sro.sussex.ac.uk/id/eprint/74951/ http://sro.sussex.ac.uk/id/eprint/74951/ Almohammed, Rajaei, Osborn, Kay, Ramasubramanyan, Sharada, Naranjo Perez-Fernandez, Ijiel Barak, Godfrey, Anja, Mancini, Erika J and Sinclair, Alison J (2018) Mechanism of activation of the BNLF2a immune evasion gene of Epstein-Barr virus by Zta. Journal of General Virology, 99. pp. 805-817. ISSN 0022-1317 Mon, 26 Mar 2018 08:29:05 +0100 Evolution of the POU1F1 transcription factor in mammals: rapid change of the alternatively-spliced β-domain http://sro.sussex.ac.uk/id/eprint/74627/ http://sro.sussex.ac.uk/id/eprint/74627/ Wallis, Michael (2018) Evolution of the POU1F1 transcription factor in mammals: rapid change of the alternatively-spliced β-domain. General and Comparative Endocrinology, 260. pp. 100-106. ISSN 0016-6480 Wed, 21 Mar 2018 11:38:32 +0000 Investigating the spatial regulation of meiotic recombination in S. cerevisiae http://sro.sussex.ac.uk/id/eprint/74309/ http://sro.sussex.ac.uk/id/eprint/74309/ Cooper, Timothy J. (2018) Investigating the spatial regulation of meiotic recombination in S. cerevisiae. Doctoral thesis (PhD), University of Sussex. Mon, 19 Mar 2018 12:18:24 +0000 LMTK3 confers chemo-resistance in breast cancer http://sro.sussex.ac.uk/id/eprint/74487/ http://sro.sussex.ac.uk/id/eprint/74487/ Stebbing, Justin, Shah, Kalpit, Lit, Lei Cheng, Gagliano, Teresa, Ditsiou, Angeliki, Wang, Tingting, Wendler, Franz, Simon, Thomas, Szabo, Krisztina Sára, O’Hanlon, Timothy, Dean, Michael, Roslani, April Camilla, Cheah, Swee Hung, Lee, Soo-Chin and Giamas, Georgios (2018) LMTK3 confers chemo-resistance in breast cancer. Oncogene, 37 (23). pp. 3113-3130. ISSN 1476-5594 Thu, 08 Mar 2018 10:58:10 +0000 Combined 1H-Detected solid-state NMR spectroscopy and electron cryotomography to study membrane proteins across resolutions in native environments http://sro.sussex.ac.uk/id/eprint/71682/ http://sro.sussex.ac.uk/id/eprint/71682/ Baker, Lindsay A, Sinnige, Tessa, Schellenberger, Pascale, de Keyzer, Jeanine, Siebert, C Alistair, Driessen, Arnold J M, Baldus, Marc and Grünewald, Kay (2018) Combined 1H-Detected solid-state NMR spectroscopy and electron cryotomography to study membrane proteins across resolutions in native environments. Structure, 26 (1). pp. 161-170. ISSN 0969-2126 Mon, 19 Feb 2018 16:20:58 +0000 Optimal scaling and contingency tables reveal the mismatch between patients’ attitude and perception towards their asthma medications and complaints during the I-MUR service provision http://sro.sussex.ac.uk/id/eprint/73699/ http://sro.sussex.ac.uk/id/eprint/73699/ Manfrin, Andrea, Mar Molinero, Cecilio and Krska, Janet (2018) Optimal scaling and contingency tables reveal the mismatch between patients’ attitude and perception towards their asthma medications and complaints during the I-MUR service provision. In: 5th Stochastic Modeling Techniques and Data Analysis International Conference, 12-15 June 2018, Chania, Crete, Greece. Tue, 30 Jan 2018 09:03:30 +0000 Pumilio directs deadenylation-associated translational repression of the cyclin-dependent kinase 1 activator RGC-32 http://sro.sussex.ac.uk/id/eprint/73206/ http://sro.sussex.ac.uk/id/eprint/73206/ Brocard, Michèle, Khasnis, Sarika, Wood, C David, Shannon-Lowe, Claire and West, Michelle J (2018) Pumilio directs deadenylation-associated translational repression of the cyclin-dependent kinase 1 activator RGC-32. Nucleic Acids Research, 46 (7). pp. 3707-3725. ISSN 0305-1048 Tue, 23 Jan 2018 09:23:11 +0000 Characterization of an influenza virus pseudotyped with Ebolavirus glycoprotein http://sro.sussex.ac.uk/id/eprint/73064/ http://sro.sussex.ac.uk/id/eprint/73064/ Xiao, Julie, Rijal, Pramila, Schimanski, Lisa, Tharkeshwar, Arun Kumar, Wright, Edward, Annaert, Wim and Townsend, Alain (2018) Characterization of an influenza virus pseudotyped with Ebolavirus glycoprotein. Journal of Virology, 92 (5). ISSN 0022-538X Tue, 23 Jan 2018 09:15:39 +0000 Antigenic site changes in the rabies virus glycoprotein dictates functionality and neutralizing capability against divergent lyssaviruses http://sro.sussex.ac.uk/id/eprint/73061/ http://sro.sussex.ac.uk/id/eprint/73061/ Evans, J S, Selden, D, Wu, G, Wright, E, Horton, D L, Fooks, A R and Banyard, A C (2018) Antigenic site changes in the rabies virus glycoprotein dictates functionality and neutralizing capability against divergent lyssaviruses. Journal of General Virology, 99. pp. 169-180. ISSN 0022-1317 Mon, 22 Jan 2018 10:54:47 +0000 Multi-chaperone function modulation and association with cytoskeletal proteins are key features of the function of AIP in the pituitary gland http://sro.sussex.ac.uk/id/eprint/73044/ http://sro.sussex.ac.uk/id/eprint/73044/ Hernández-Ramírez, Laura C, Morgan, Rhodri M L, Barry, Sayka, D’Acquisto, Fulvio, Prodromou, Chrisostomos and Korbonits, Márta (2018) Multi-chaperone function modulation and association with cytoskeletal proteins are key features of the function of AIP in the pituitary gland. Oncotarget, 9 (10). pp. 9177-9198. ISSN 1949-2553 Wed, 17 Jan 2018 10:37:26 +0000 The stoichiometric interaction of the Hsp90-Sgt1-Rar1 complex by CD and SRCD spectroscopy http://sro.sussex.ac.uk/id/eprint/71749/ http://sro.sussex.ac.uk/id/eprint/71749/ Siligardi, Giuliano, Zhang, Minghao and Prodromou, Chrisostomos (2018) The stoichiometric interaction of the Hsp90-Sgt1-Rar1 complex by CD and SRCD spectroscopy. Frontiers in Molecular Biosciences, 4 (95). pp. 1-13. ISSN 2296-889X Wed, 17 Jan 2018 08:31:11 +0000 The Anatomical Society core anatomy syllabus for pharmacists: outcomes to create a foundation for practice http://sro.sussex.ac.uk/id/eprint/72888/ http://sro.sussex.ac.uk/id/eprint/72888/ Finn, Gabrielle M, Hitch, Geeta, Apampa, Buge, Hennessy, Catherine M, Smith, Claire F, Stewart, Jane and Gard, Paul R (2018) The Anatomical Society core anatomy syllabus for pharmacists: outcomes to create a foundation for practice. Journal of Anatomy, 232 (5). pp. 729-738. ISSN 0021-8782 Mon, 15 Jan 2018 13:15:02 +0000 Pharmacists’ and patients’ views and feedback on Italian Medicines Use Review (I-MUR) http://sro.sussex.ac.uk/id/eprint/72820/ http://sro.sussex.ac.uk/id/eprint/72820/ Manfrin, Andrea and Krska, J (2018) Pharmacists’ and patients’ views and feedback on Italian Medicines Use Review (I-MUR). European Journal for Person Centered Healthcare, 6 (2). pp. 286-296. ISSN 2052-5648 Mon, 15 Jan 2018 12:51:52 +0000 VP164 Applying health technology assessment to pharmacy: the Italian-Medicine-Use-Review-Health Technology Assessment http://sro.sussex.ac.uk/id/eprint/72819/ http://sro.sussex.ac.uk/id/eprint/72819/ Manfrin, Andrea, Knapp, Martin, Cicchetti, Americo, Mandelli, Andrea and Tinelli, Michela (2018) VP164 Applying health technology assessment to pharmacy: the Italian-Medicine-Use-Review-Health Technology Assessment. HATi, Rome Italy. Published in: International Journal of Technology Assessment in Health Care. 33 (S1) 223-224. Cambridge University Press ISSN 0266-4623 Wed, 10 Jan 2018 09:08:15 +0000 Optimal scaling and contingency tables reveal the mismatch between patients’ attitude and perception towards their asthma medications and complaints during the I-MUR service provision http://sro.sussex.ac.uk/id/eprint/72669/ http://sro.sussex.ac.uk/id/eprint/72669/ Manfrin, Andrea, Mar Molinero, Cecilio and Krska, Janet (2018) Optimal scaling and contingency tables reveal the mismatch between patients’ attitude and perception towards their asthma medications and complaints during the I-MUR service provision. 5th Stochastic Modeling Techniques and Data Analysis International Conference, Chania, Crete, Greece, 12-15 June 2018. Published in: Skiadas, Christos H, (ed.) Stochastic Modeling Techniques and Data Analysis International Conference with Demographic Workshop SMTDA 2018. 399-408. ISAST: International Society for the Advancement of Science and Technology. Thu, 31 Aug 2017 08:06:07 +0100 Temperature-dependent development of Helicoverpa armigera (Hübner) (Lepidoptera: Noctuidae) and its larval parasitoid, Habrobracon hebetor (Say) (Hymenoptera: Braconidae): implications for species interactions http://sro.sussex.ac.uk/id/eprint/69941/ http://sro.sussex.ac.uk/id/eprint/69941/ Noor-ul-Ane, M, Ali Mirhosseini, M, Crickmore, Neil, Saeed, S, Noor, I and Zalucki, M P (2018) Temperature-dependent development of Helicoverpa armigera (Hübner) (Lepidoptera: Noctuidae) and its larval parasitoid, Habrobracon hebetor (Say) (Hymenoptera: Braconidae): implications for species interactions. Bulletin of Entomological Research, 108 (3). pp. 295-304. ISSN 0007-4853