http://sro.sussex.ac.uk/ http://sro.sussex.ac.uk/images/sitelogo.png http://sro.sussex.ac.uk/ Tue, 21 Nov 2023 10:17:58 +0000 Tue, 21 Nov 2023 10:17:58 +0000 en Tue, 28 Nov 2017 16:28:14 +0000 http://sro.sussex.ac.uk/id/eprint/64162/ http://sro.sussex.ac.uk/id/eprint/64162/ Nokhodchi, A, Shokri, J, Dashbolaghi, A, Hassan-Zadeh, D, Ghafourian, T and Barzegar-Jalali, M (2003) The enhancement effect of surfactants on the penetration of lorazepam through rat skin. International Journal of Pharmaceutics, 250 (2). pp. 359-369. ISSN 0378-5173 Tue, 28 Nov 2017 14:59:59 +0000 http://sro.sussex.ac.uk/id/eprint/64161/ http://sro.sussex.ac.uk/id/eprint/64161/ Abraham, Michael H, Hassanisadi, Mostafa, Jalali-Heravi, Mehdi, Ghafourian, Taravat, Cain, William S and Cometto-Muñiz, J Enrique (2003) Draize rabbit eye test compatibility with eye irritation thresholds in humans: a quantitative structure-activity relationship analysis. Toxicological Sciences, 76 (2). pp. 384-391. ISSN 1096-6080 Wed, 22 Jul 2015 13:08:24 +0100 http://sro.sussex.ac.uk/id/eprint/55637/ http://sro.sussex.ac.uk/id/eprint/55637/ Lynch, Anthony, Harvey, James, Aylott, Michael, Nicholas, Emma, Burman, Mark, Siddiqui, Ayesha, Walker, Sarah and Rees, Robert (2003) Investigations into the concept of a threshold for topoisomerase inhibitor-induced clastogenicity. Mutagenesis, 18 (4). pp. 345-53. ISSN 0267-8357 Wed, 25 Mar 2015 11:45:21 +0000 http://sro.sussex.ac.uk/id/eprint/52611/ http://sro.sussex.ac.uk/id/eprint/52611/ Royle, Stephen J and Murrell-Lagnado, Ruth D (2003) Constitutive cycling: a general mechanism to regulate cell surface proteins. BioEssays, 25 (1). pp. 39-46. ISSN 0265-9247 Wed, 25 Feb 2015 08:55:58 +0000 http://sro.sussex.ac.uk/id/eprint/44356/ http://sro.sussex.ac.uk/id/eprint/44356/ Piper, Peter W, Panaretou, Barry, Millson, Stefan H, Truman, Andrew, Mollapour, Mehdi, Pearl, Laurence and Prodromou, Chrisostomos (2003) Yeast is selectively hypersensitised to heat shock protein 90 (Hsp90)-targetting drugs with heterologous expression of the human Hsp90beta, a property that can be exploited in screens for new Hsp90 chaperone inhibitors. Gene, 302 (1-2). pp. 165-170. ISSN 0378-1119 Wed, 25 Feb 2015 08:43:54 +0000 http://sro.sussex.ac.uk/id/eprint/44355/ http://sro.sussex.ac.uk/id/eprint/44355/ Piper, Peter W, Millson, Stefan H, Mollapour, Mehdi, Panaretou, Barry, Siligardi, Giuliano, Pearl, Laurence H and Prodromou, Chrisostomos (2003) Sensitivity to Hsp90-targeting drugs can arise with mutation to the Hsp90 chaperone, cochaperones and plasma membrane ATP binding cassette transporters of yeast. European Journal of Biochemistry, 270 (23). pp. 4689-4695. ISSN 0014-2956 Wed, 25 Feb 2015 07:01:42 +0000 http://sro.sussex.ac.uk/id/eprint/44340/ http://sro.sussex.ac.uk/id/eprint/44340/ Meyer, Philipe, Prodromou, Chrisostomos, Hu, Bin, Vaughan, Cara, Roe, S Mark, Panaretou, Barry, Piper, Peter W and Pearl, Laurence H (2003) Structural and functional analysis of the middle segment of hsp90: implications for ATP hydrolysis and client protein and cochaperone interactions. Molecular Cell, 11 (3). pp. 647-658. ISSN 1097-2765 Wed, 25 Feb 2015 06:50:34 +0000 http://sro.sussex.ac.uk/id/eprint/44331/ http://sro.sussex.ac.uk/id/eprint/44331/ Aherne, Wynne, Maloney, Alison, Prodromou, Chrisostomos, Rowlands, Martin G, Hardcastle, Anthea, Boxall, Katherine, Clarke, Paul, Walton, Michael I, Pearl, Laurence and Workman, Paul (2003) Assays for HSP90 and inhibitors. Methods in Molecular Medicine, 85. pp. 149-161. ISSN 1543-1894 Tue, 24 Feb 2015 17:41:13 +0000 http://sro.sussex.ac.uk/id/eprint/44362/ http://sro.sussex.ac.uk/id/eprint/44362/ Prodromou, Chrisostomos and Pearl, Laurence H (2003) Structure and functional relationships of Hsp90. Current Cancer Drug Targets, 3 (5). pp. 301-323. ISSN 1568-0096 Thu, 29 Jan 2015 11:33:40 +0000 http://sro.sussex.ac.uk/id/eprint/52565/ http://sro.sussex.ac.uk/id/eprint/52565/ Brown, J, Walter, T S, Carter, L, Abrescia, N G A, Aricescu, A R, Batuwangala, T D, Bird, L E, Brown, N, Chamberlain, P P, Davis, S J, Dubinina, E, Endicott, J, Fennelly, J A, Gilbert, R J C, Harkiolaki, M, Hon, W-C, Kimberley, F, Love, C A, Mancini, E J, Manso-Sancho, R, Nichols, C E, Robinson, R A, Sutton, G C, Schueller, N, Sleeman, M C, Stewart-Jones, G B, Vuong, M, Welburn, J, Zhang, Z, Stammers, D K, Owens, R J, Jones, E Y, Harlos, K and Stuart, D I (2003) A procedure for setting up high-throughput nanolitre crystallization experiments. II. Crystallization results. Journal of Applied Crystallography, 36 (2). pp. 315-318. ISSN 0021-8898 Thu, 29 Jan 2015 10:40:23 +0000 http://sro.sussex.ac.uk/id/eprint/52564/ http://sro.sussex.ac.uk/id/eprint/52564/ Mancini, E J, Grimes, J M, Malby, R, Sutton, G C, Kainov, D E, Juuti, J T, Makeyev, E V, Tuma, R, Bamford, D H and Stuart, D I (2003) Order and disorder in crystals of hexameric NTPases from dsRNA bacteriophages. Acta Crystallographica Section D: Biological Crystallography, 59 (12). pp. 2337-2341. ISSN 0907-4449 Mon, 06 Feb 2012 21:24:48 +0000 http://sro.sussex.ac.uk/id/eprint/31134/ http://sro.sussex.ac.uk/id/eprint/31134/ de Maagd, Ruud A, Bravo, Alejandra, Berry, Colin, Crickmore, Neil and Schnepf, H Ernest (2003) Structure, diversity, and evolution of protein toxins from spore-forming entomopathogenic bacteria. Annual Review of Genetics, 37. pp. 409-433. ISSN 0066-4197 Mon, 06 Feb 2012 21:09:53 +0000 http://sro.sussex.ac.uk/id/eprint/29887/ http://sro.sussex.ac.uk/id/eprint/29887/ Sinclair, Alison J. (2003) bZIP proteins of human gammaherpesviruses. Journal of General Virology, 84 (8). pp. 1941-1949. ISSN 0022-1317 Mon, 06 Feb 2012 21:09:29 +0000 http://sro.sussex.ac.uk/id/eprint/29842/ http://sro.sussex.ac.uk/id/eprint/29842/ Jones, Rhiannon E, Chapman, J Ross, Puligilla, Chandrakala, Murray, Johanne M, Carr, Antony M, Ford, Christopher C and Lindsay, Howard D (2003) XRad17 Is Required for the Activation of XChk1 But Not XCds1 during Checkpoint Signaling in Xenopus. Molecular Biology of the Cell, 14 (9). pp. 3898-3910. ISSN 1059-1524 Mon, 06 Feb 2012 21:08:31 +0000 http://sro.sussex.ac.uk/id/eprint/29739/ http://sro.sussex.ac.uk/id/eprint/29739/ Sikorski, Pawel, Atkins, Edward D T and Serpell, Louise C (2003) Structure and textures of fibrous crystals of the Abeta (11-25) peptide fragment from Alzheimer's Abeta Amyloid protein. Structure, 11 (1). pp. 1-2. ISSN 0969-2126 Mon, 06 Feb 2012 21:08:18 +0000 http://sro.sussex.ac.uk/id/eprint/29716/ http://sro.sussex.ac.uk/id/eprint/29716/ Paget, Mark and Helmann, John (2003) Protein family review - The sigma(70) family of sigma factors. Genome Biology, 4 (1). ISSN 1465-6906 Mon, 06 Feb 2012 21:01:01 +0000 http://sro.sussex.ac.uk/id/eprint/29108/ http://sro.sussex.ac.uk/id/eprint/29108/ Berriman, John, Serpell, Louise C, Oberg, Keith A, Fink, Anthony L, Goedert, Michel and Crowther, R Anthony (2003) Tau filaments from human brain and from in vitro assembly of recombinant protein show cross-ß structure. Proceedings of the National Academy of Sciences, 100 (15). pp. 9034-9038. ISSN 0027-8424 Mon, 06 Feb 2012 20:56:47 +0000 http://sro.sussex.ac.uk/id/eprint/28798/ http://sro.sussex.ac.uk/id/eprint/28798/ Harris, Sheila, Kemplen, Caroline, Caspari, Thomas, Chan, Christopher, Lindsay, Howard D, Poitelea, Marius, Carr, Antony M and Price, Clive (2003) Delineating the position of rad4+/cut5+ within the DNA-structure checkpoint pathways in Schizosaccharomyces pombe. Journal of Cell Science, 116 (17). pp. 3519-3529. ISSN 0021-9533 Mon, 06 Feb 2012 20:48:50 +0000 http://sro.sussex.ac.uk/id/eprint/28258/ http://sro.sussex.ac.uk/id/eprint/28258/ Ueno, Masaru, Nakazaki, Tomofumi, Akamatsu, Yufuko, Watanabe, Kikuo, Tomita, Kazunori, Lindsay, Howard D, Shinagawa, Hideo and Iwasaki, Hiroshi (2003) Molecular characterization of the Schizosaccharomyces pombe nbs1+ gene involved in DNA repair and telomere maintenance. Molecular and Cellular Biology, 23 (18). pp. 6553-6563. ISSN 0270-7306 Mon, 06 Feb 2012 20:37:19 +0000 http://sro.sussex.ac.uk/id/eprint/27019/ http://sro.sussex.ac.uk/id/eprint/27019/ Bone, N, Nurse, P and Armstrong, J (2003) VTC4: a regulator of vacuole size in fission yeast. In: 21st International Conference on Yeast Genetics and Molecular Biology, JUL 07-12, 2003, Gothenburg, Sweden. Mon, 06 Feb 2012 20:35:09 +0000 http://sro.sussex.ac.uk/id/eprint/26777/ http://sro.sussex.ac.uk/id/eprint/26777/ Jones, Susan, Barker, Jonathan A, Nobeli, Irene and Thornton, Janet M (2003) Using structural motifs to identify proteins with DNA binding function. Nucleic Acids Research, 31 (11). pp. 2811-2823. ISSN 0305-1048 Mon, 06 Feb 2012 20:26:41 +0000 http://sro.sussex.ac.uk/id/eprint/25927/ http://sro.sussex.ac.uk/id/eprint/25927/ Brekasis, Dimitris and Paget, Mark S B (2003) A novel sensor of NADH/NAD+ redox poise in Streptomyces coelicolor A3(2). EMBO Journal, 22 (18). pp. 4856-4865. ISSN 0261-4189 Mon, 06 Feb 2012 20:22:39 +0000 http://sro.sussex.ac.uk/id/eprint/25650/ http://sro.sussex.ac.uk/id/eprint/25650/ Amoah-Buahin, Evelyn, Ramdath, Ramona, Antoniadi, Thalia, Bone, Neil and Armstrong, John (2003) Schizosaccharomyces pombe: a dimorphic fission yeast. In: 21st International Conference on Yeast Genetics and Molecular Biology, JUL 07-12, 2003, GOTHENBURG, SWEDEN. Mon, 06 Feb 2012 20:17:21 +0000 http://sro.sussex.ac.uk/id/eprint/25176/ http://sro.sussex.ac.uk/id/eprint/25176/ Jenkinson, Elizabeth and Crickmore, Neil (2003) Identification of a novel DNA methyltransferase activity from Bacillus thuringiensis. Current Microbiology, 47 (2). pp. 144-145. ISSN 0343-8651 Mon, 06 Feb 2012 20:10:27 +0000 http://sro.sussex.ac.uk/id/eprint/24440/ http://sro.sussex.ac.uk/id/eprint/24440/ Morley, Simon J and Naegele, Susanne (2003) Phosphorylation of initiation factor 4E is resistant to SB203580 in cells expressing a drug-resistant mutant of stress-activated protein kinase 2a/p38. Cellular Signalling, 15 (8). pp. 741-749. ISSN 0898-6568 Mon, 06 Feb 2012 20:09:12 +0000 http://sro.sussex.ac.uk/id/eprint/24317/ http://sro.sussex.ac.uk/id/eprint/24317/ Butler, Miranda J, Jacobsen, Thomas L, Cain, Donna M, Jarman, Michael G, Hubank, Michael, Whittle, J Robert S, Phillips, Roger and Simcox, Amanda (2003) Discovery of genes with highly restricted expression patterns in the Drosophila wing disc using DNA oligonucleotide microarrays. Development, 130. pp. 659-670. ISSN 0950-1991 Mon, 06 Feb 2012 19:57:53 +0000 http://sro.sussex.ac.uk/id/eprint/23234/ http://sro.sussex.ac.uk/id/eprint/23234/ Walsh, Derek, Meleady, Paula, Power, Brendan, Morley, Simon J and Clynes, Martin (2003) Increased levels of the translation initiation factor eIF4E in differentiating epithelial lung tumor cell lines. Differentiation, 71 (2). pp. 126-134. ISSN 0301-4681 Mon, 06 Feb 2012 19:54:52 +0000 http://sro.sussex.ac.uk/id/eprint/22931/ http://sro.sussex.ac.uk/id/eprint/22931/ Hashemzadeh-Bonehi, Lida, Curtis, Penelope S, Morley, Simon J, Thorpe, Julian R and Pain, Virginia M (2003) Overproduction of a conserved domain of fission yeast and mammalian translation initiation factor eIF4G causes aberrant cell morphology and results in disruption of the localization of F-actin and the organization of microtubules. Genes to Cells, 8 (2). pp. 163-178. ISSN 1356-9597 Mon, 06 Feb 2012 19:51:19 +0000 http://sro.sussex.ac.uk/id/eprint/22548/ http://sro.sussex.ac.uk/id/eprint/22548/ Spriggs, Ruth V, Artymiuk, Peter J and Willett, Peter (2003) Searching for patterns of amino acids in 3D protein structures. Journal of Chemical Information and Computer Sciences, 43 (2). pp. 412-421. ISSN 0095-2338 Mon, 06 Feb 2012 19:50:22 +0000 http://sro.sussex.ac.uk/id/eprint/22442/ http://sro.sussex.ac.uk/id/eprint/22442/ Li, Wei, Bottrill, Andrew R, Bibb, Maureen J, Buttner, Mark J, Paget, Mark S B and Kleanthous, Colin (2003) The Role of Zinc in the Disulfide Stress-Regulated Anti-Sigma Factor RsrA from Streptomyces coelicolor. Journal of Molecular Biology, 333 (2). pp. 461-472. ISSN 0022-2836 Mon, 06 Feb 2012 19:50:02 +0000 http://sro.sussex.ac.uk/id/eprint/22407/ http://sro.sussex.ac.uk/id/eprint/22407/ Reynolds, Lindsey, Ullman, Christopher, Moore, Michael, Isalan, Mark, West, Michelle J, Clapham, Paul, Klug, Aaron and Choo, Yen (2003) Repression of the HIV-1 5' LTR promoter and inhibition of HIV-1 replication by using engineered zinc-finger transcription factors. Proceedings of the National Academy of Sciences, 100 (4). pp. 1615-1620. ISSN 0027-8424 Mon, 06 Feb 2012 19:45:32 +0000 http://sro.sussex.ac.uk/id/eprint/22061/ http://sro.sussex.ac.uk/id/eprint/22061/ Paget, Mark S B and Buttner, Mark J (2003) Thiol-based regulatory switches. Annual Review Genetics, 37. pp. 91-121. ISSN 0066-4197 Mon, 06 Feb 2012 19:30:50 +0000 http://sro.sussex.ac.uk/id/eprint/20955/ http://sro.sussex.ac.uk/id/eprint/20955/ Hicks, Matthew R., Al-Mehairi, Salama S. and Sinclair, Alison J. (2003) The Zipper Region of Epstein-Barr Virus bZIP Transcription Factor Zta Is Necessary but Not Sufficient To Direct DNA Binding. Journal of Virology, 77 (14). pp. 8173-8177. ISSN 0022-538X Mon, 06 Feb 2012 18:49:39 +0000 http://sro.sussex.ac.uk/id/eprint/18509/ http://sro.sussex.ac.uk/id/eprint/18509/ Smith, David P, Jones, Susan, Serpell, Louise C, Sunde, Margaret and Radford, Sheena E (2003) A Systematic Investigation into the Effect of Protein Destabilisation on Beta 2-Microglobulin Amyloid Formation. Journal of Molecular Biology, 330 (5). pp. 943-954. ISSN 0022-2836 Mon, 06 Feb 2012 18:40:40 +0000 http://sro.sussex.ac.uk/id/eprint/17707/ http://sro.sussex.ac.uk/id/eprint/17707/ Paget, Mark S B and Helmann, John D (2003) The Sig70 family of sigma factors. Genome Biology, 4 (1). ISSN 1465-6906 Mon, 06 Feb 2012 18:35:20 +0000 http://sro.sussex.ac.uk/id/eprint/17272/ http://sro.sussex.ac.uk/id/eprint/17272/ Crowther, Damian C, Serpell, Louise C, Daffron, Timothy R, Gooptu, Bibek and Lomas, David A (2003) Nucleation of alpha1-Antichymotrypsin Polymerization. Biochemistry, 42 (8). pp. 2355-2363. ISSN 0006-2960 Mon, 06 Feb 2012 18:26:37 +0000 http://sro.sussex.ac.uk/id/eprint/16358/ http://sro.sussex.ac.uk/id/eprint/16358/ Taylor, D L, Ward, P N, Leigh, J A and Bowler, L D (2003) Identification of a Differentially Expressed Oligopeptide Binding Protein (OppA2) in Streptococcus uberis by Representational Difference Analysis of cDNA. Journal of Bacteriology, 185 (17). pp. 5210-9. ISSN 0021-9193 Mon, 06 Feb 2012 18:20:09 +0000 http://sro.sussex.ac.uk/id/eprint/15829/ http://sro.sussex.ac.uk/id/eprint/15829/ Jones, Susan, Shanahan, Hugh P, Berman, Helen M and Thornton, Janet M (2003) Using electrostatic potentials to predict DNA-binding sites on DNA-binding proteins. Nucleic Acids Research, 31 (24). pp. 7189-7198. ISSN 0305-1048 http://sro.sussex.ac.uk/id/eprint/1314/ http://sro.sussex.ac.uk/id/eprint/1314/ Hedgecoe, Adam and Martin, Paul (2003) The Drugs Don't Work: Expectations and the Shaping of Pharmacogenetics. Social Studies of Science, 33 (3). pp. 327-364. ISSN 1460-3659 http://sro.sussex.ac.uk/id/eprint/577/ http://sro.sussex.ac.uk/id/eprint/577/ d'Adda di Fagagna, Fabrizio, Weller, Geoffrey R, Doherty, Aidan and Jackson, Stephen P (2003) The Gam protein of bacteriophage Mu is an orthologue of eukaryotic Ku. EMBO Reports, 4 (1). pp. 47-52. ISSN 1469-221X