Sussex Research Online: No conditions. Results ordered -Date Deposited. http://sro.sussex.ac.uk/ http://sro.sussex.ac.uk/images/sitelogo.png Sussex Research Online: No conditions. Results ordered -Date Deposited. http://sro.sussex.ac.uk/ Sun, 26 Nov 2023 04:03:17 +0000 Sun, 26 Nov 2023 04:03:17 +0000 en Fri, 24 Jul 2020 07:55:14 +0100 Synthesis and biological evaluation of JAHAs: ferrocene-based histone deacetylase inhibitors http://sro.sussex.ac.uk/id/eprint/92730/ http://sro.sussex.ac.uk/id/eprint/92730/ Spencer, John, Amin, Jahangir, Wang, Minghua, Packham, Graham, Alwi, Sharifah S S, Tizzard, Graham J, Coles, Simon J, Paranal, Ronald M, Bradner, James E and Heightman, Tom D (2011) Synthesis and biological evaluation of JAHAs: ferrocene-based histone deacetylase inhibitors. ACS Medicinal Chemistry Letters, 2 (5). pp. 358-362. ISSN 1948-5875 Tue, 23 Feb 2016 10:30:48 +0000 A poised fragment library enables rapid synthetic expansion yielding the first reported inhibitors of PHIP(2), an atypical bromodomain http://sro.sussex.ac.uk/id/eprint/59737/ http://sro.sussex.ac.uk/id/eprint/59737/ Cox, Oakley B, Krojer, Tobias, Collins, Patrick, Monteiro, Octovia, Talon, Romain, Bradley, Anthony, Fedorov, Oleg, Amin, Jahangir, Marsden, Brian D, Spencer, John, von Delft, Frank and Brennan, Paul E (2016) A poised fragment library enables rapid synthetic expansion yielding the first reported inhibitors of PHIP(2), an atypical bromodomain. Chemical Science, 7 (3). pp. 2322-2330. ISSN 2041-6520 Tue, 30 Sep 2014 11:15:52 +0100 A cyclodextrin-capped histone deacetylase inhibitor http://sro.sussex.ac.uk/id/eprint/50419/ http://sro.sussex.ac.uk/id/eprint/50419/ Amin, Jahangir, Puglisi, Antonio, Clarke, James, Milton, John, Wang, Minghua, Paranal, Ronald M, Bradner, James E and Spencer, John (2013) A cyclodextrin-capped histone deacetylase inhibitor. Bioorganic and Medicinal Chemistry Letters, 23 (11). pp. 3346-3348. ISSN 0960-894X Tue, 30 Sep 2014 11:10:58 +0100 Synthesis of oxindole-based bioorganometallic kinase inhibitors incorporating one or more ferrocene groups http://sro.sussex.ac.uk/id/eprint/50418/ http://sro.sussex.ac.uk/id/eprint/50418/ Amin, Jahangir, Chuckowree, Irina, Wang, Minghua, Tizzard, Graham J, Coles, Simon J and Spencer, John (2013) Synthesis of oxindole-based bioorganometallic kinase inhibitors incorporating one or more ferrocene groups. Organometallics, 32 (20). pp. 5818-5825. ISSN 0276-7333 Tue, 30 Apr 2013 09:38:23 +0100 Small molecule induced reactivation of mutant p53 in cancer cells http://sro.sussex.ac.uk/id/eprint/44541/ http://sro.sussex.ac.uk/id/eprint/44541/ Liu, Xiangrui, Wilcken, Rainer, Joerger, Andreas C, Chuckowree, Irina S, Amin, Jahangir, Spencer, John and Fersht, Alan R (2013) Small molecule induced reactivation of mutant p53 in cancer cells. Nucleic Acids Research, 41 (12). pp. 6034-6044. ISSN 0305-1048