Sussex Research Online: No conditions. Results ordered -Date Deposited.

Erbb4 deletion from inhibitory interneurons causes psychosis-relevant neuroimaging phenotypes

Fri, 19 May 2023 09:32:43 +0100

Kiemes, Amanda, Serrano Navacerrada, Maria Elisa, Kim, Eugene, Randall, Karen, Simmons, Camilla, Rojo Gonzalez, Loreto, Petrinovic, Marija-Magdalena, Lythgoe, David J, Rotaru, Diana, Di Censo, Davide, Hirschler, Lydiane, Barbier, Emmanuel L, Vernon, Anthony C, Stone, James M, Davies, Cathy, Cash, Diana and Modinos, Gemma (2023) Erbb4 deletion from inhibitory interneurons causes psychosis-relevant neuroimaging phenotypes. Schizophrenia Bulletin, 49. pp. 569-580. ISSN 1787-9965

Prediction of transition to psychosis from an at-risk mental state using structural neuroimaging, genetic, and environmental data

Fri, 19 May 2023 09:21:30 +0100

Tavares, Vânia, Vassos, Evangelos, Marquand, Andre, Stone, James, Valli, Isabel, Barker, Gareth J, Ferreira, Hugo and Prata, Diana (2022) Prediction of transition to psychosis from an at-risk mental state using structural neuroimaging, genetic, and environmental data. Front Psychiatry, 13. a1086038. ISSN 1664-0640

Variants in the zinc transporter-3 encoding gene (SLC30A3) in schizophrenia and bipolar disorder: effects on brain glutamate–A pilot study

Fri, 28 Oct 2022 14:00:15 +0100

Jelen, Luke A, Green, Mark S, King, Sinead, Morris, Alex G, Zhang, Xinyuan, Lythgoe, David J, Young, Allan H, De Belleroche, Jaqueline and Stone, James M (2022) Variants in the zinc transporter-3 encoding gene (SLC30A3) in schizophrenia and bipolar disorder: effects on brain glutamate–A pilot study. Frontiers in Psychiatry, 13. a929306 1-11. ISSN 1664-0640

The association between N-methyl-d-aspartate receptor availability and glutamate levels: A multi-modal PET-MR brain imaging study in first-episode psychosis and healthy controls

Fri, 28 Oct 2022 13:49:37 +0100

Beck, Katherine, Arumuham, Atheeshaan, Brugger, Stefan, McCutcheon, Robert A, Veronese, Mattia, Santangelo, Barbara, McGinnity, Colm J, Dunn, Joel, Kaar, Stephen, Singh, Nisha, Pillinger, Toby, Borgan, Faith, Sementa, Teresa, Neji, Radhouene, Jauhar, Sameer, Aigbirhio, Franklin, Boros, Istvan, Turkheimer, Federico, Hammers, Alexander, Lythgoe, David, Stone, James and Howes, Oliver D (2022) The association between N-methyl-d-aspartate receptor availability and glutamate levels: A multi-modal PET-MR brain imaging study in first-episode psychosis and healthy controls. Journal of Psychopharmacology, 36 (9). pp. 1051-1060. ISSN 0269-8811

Clinical, cognitive and neuroanatomical associations of serum NMDAR autoantibodies in people at clinical high risk for psychosis

Mon, 03 Oct 2022 14:57:32 +0100

Pollak, Thomas A, Kempton, Matthew J, Iyegbe, Conrad, Vincent, Angela, Irani, Sarosh R, Coutinho, Ester, Menassa, David A, Jacobson, Leslie, de Haan, Lieuwe, Ruhrmann, Stephan, Sachs, Gabriele, Riecher-Rössler, Anita, Krebs, Marie-Odile, Amminger, Paul and Stone, James (2021) Clinical, cognitive and neuroanatomical associations of serum NMDAR autoantibodies in people at clinical high risk for psychosis. Molecular Psychiatry, 26. pp. 2590-2604. ISSN 1359-4184

Relationship between serum NMDA receptor antibodies and response to antipsychotic treatment in first-episode psychosis

Mon, 03 Oct 2022 14:46:19 +0100

Pollak, Thomas A, Vincent, Anegla, Iyegbe, Conrad, Coutinho, Ester, Jacobson, Leslie, Rujescu, Dan, Stone, James, Jezequel, Julie, Rogemond, Veronique, Jamain, Stephane, Groc, Laurent, David, Anthony, Egerton, Alice, Kahn, Rene S, Honnorat, Jerome, Dazzan, Paola, Leboyer, Marion and McGuire, Philip (2021) Relationship between serum NMDA receptor antibodies and response to antipsychotic treatment in first-episode psychosis. Biological Psychiatry, 90 (1). pp. 9-15. ISSN 0006-3223

Integrated metastate functional connectivity networks predict change in symptom severity in clinical high risk for psychosis

Mon, 03 Oct 2022 14:41:07 +0100

Gifford, George, Crossley, Nicholas, Morgan, Sarah, Kempton, Matthew J, Dazzan, Paola, Modinos, Gemma, Azis, Matilda, Samson, Carly, Bonoldi, Ilaria, Quinn, Beverly, Smart, Sophie E, Antoniades, Mathilde, Bossong, Mattijis G, Broome, Matthew R, Perez, Jesus, Howes, Oliver D, Stone, James M, Allen, Paul, Grace, Anthony A and McGuire, Philip (2021) Integrated metastate functional connectivity networks predict change in symptom severity in clinical high risk for psychosis. Human Brain Mapping, 42 (2). pp. 439-451. ISSN 1065-9471

Neutrophil-lymphocyte ratio across psychiatric diagnoses: a cross-sectional study using electronic health records

Mon, 03 Oct 2022 13:49:08 +0100

Brinn, Aimee and Stone, James (2020) Neutrophil-lymphocyte ratio across psychiatric diagnoses: a cross-sectional study using electronic health records. BMJ Open, 10. e036859 1-8. ISSN 2044-6055

Synthetic cannabinoid use in psychiatric patients and relationship to hospitalisation: a retrospective electronic case register study

Mon, 03 Oct 2022 13:38:53 +0100

Hobbs, Melissa, Patel, Rashmi, Morrison, Paul D, Kalk, Nicola and Stone, James M (2020) Synthetic cannabinoid use in psychiatric patients and relationship to hospitalisation: a retrospective electronic case register study. Journal of Psychopharmacology, 34 (6). pp. 648-653. ISSN 0269-8811

Neural circuitry of novelty salience processing in psychosis risk: association with clinical outcome

Mon, 03 Oct 2022 13:29:27 +0100

Modinos, Gemma, Allen, Paul, Zugman, Andre, Dima, Danai, Azis, Matilda, Samson, Carly, Bonoldi, Ilaria, Quinn, Beverly, Gifford, George W G, Smart, Sophie E, Antoniades, Mathilde, Bossong, Mattijis G, Broome, Matthew R, Perez, Jesus, Howes, Oliver D, Stone, James M, Grace, Anthony A and McGuire, Philip (2020) Neural circuitry of novelty salience processing in psychosis risk: association with clinical outcome. Schizophrenia Bulletin, 46 (3). pp. 670-679. ISSN 0586-7614

Glutamatergic and dopaminergic function and the relationship to outcome in people at clinical high risk of psychosis: a multi-modal PET-magnetic resonance brain imaging study

Mon, 03 Oct 2022 13:22:19 +0100

Howes, Oliver D, Bonoldi, Ilaria, McCutcheon, Robert A, Azis, Matlida, Antoniades, Mathilde, Bossong, Mattijis, Modinos, Gemma, Perez, Jesus, Stone, James M, Santangelo, Barbara, Veronese, Mattia, Grace, Anthony, Allen, Paul and McGuire, Philip K (2020) Glutamatergic and dopaminergic function and the relationship to outcome in people at clinical high risk of psychosis: a multi-modal PET-magnetic resonance brain imaging study. Neuropsychopharmacology, 45. pp. 641-648. ISSN 0893-133X

Effect of single dose N-acetylcysteine administration on resting state functional connectivity in schizophrenia

Mon, 03 Oct 2022 13:12:30 +0100

McQueen, Grant, Lay, Aderlee, Lally, John, Gabay, Anthony S, Collier, Tracy, Lythgoe, David J, Barker, Gareth J, Stone, James M, McGuire, Philip, MacCabe, James H and Egerton, Alice (2020) Effect of single dose N-acetylcysteine administration on resting state functional connectivity in schizophrenia. Psychopharmacology, 237. pp. 443-451. ISSN 0033-3158

Evidence-based guidelines for the pharmacological treatment of schizophrenia: updated recommendations from the British Association for Psychopharmacology

Mon, 03 Oct 2022 12:33:03 +0100

Barnes, Thomas R E, Drake, Richard, Paton, Carol, Cooper, Stephen J, Deakin, Bill, Ferrier, I Nicol, Gregory, Catherine J, Haddad, Peter M, Howes, Oliver D, Jones, Ian, Joyce, Eileen M, Lewis, Shon, Lingford-Hughes, Anne, MacCabe, James H, Owens, David C, Patel, Maxine X, Sinclair, Julia M A, Stone, James M, Talbot, Peter S, Upthegrove, Rachel, Wieck, Angelika and Yung, Alison R (2020) Evidence-based guidelines for the pharmacological treatment of schizophrenia: updated recommendations from the British Association for Psychopharmacology. Journal of Psychopharmacology, 34 (1). pp. 3-78. ISSN 0269-8811

The opioid system in depression

Mon, 03 Oct 2022 09:32:02 +0100

Jelen, Luke A, Stone, James M, Young, Allan H and Mehta, Mitul A (2022) The opioid system in depression. Neuroscience and Biobehavioral Reviews, 140. a104800 1-17. ISSN 0149-7634

The effects of antipsychotic treatment on presynaptic dopamine synthesis capacity in first-episode psychosis: a positron emission tomography study

Mon, 03 Oct 2022 09:14:10 +0100

Jauhar, Sameer, Veronese, Mattia, Nour, Matthew M, Rogdaki, Maria, Hathway, Pamela, Natesan, Sridhar, Turkheimer, Federico, Stone, James, Egerton, Alice, McGuire, Philip, Kapur, Shitij and Howes, Oliver D (2019) The effects of antipsychotic treatment on presynaptic dopamine synthesis capacity in first-episode psychosis: a positron emission tomography study. Biological Psychiatry, 85 (1). pp. 79-87. ISSN 0006-3223

Inflammation, glutamate, and cognition in bipolar disorder type II: a proof of concept study

Mon, 03 Oct 2022 09:07:57 +0100

King, Sinead, Jelen, Luke A, Horne, Charlotte M, Cleare, Anthony, Pariante, Carmine M, Young, Allan H and Stone, James M (2019) Inflammation, glutamate, and cognition in bipolar disorder type II: a proof of concept study. Frontiers in Psychiatry, 10. a66 1-6. ISSN 1664-0640

Antibodies in the diagnosis, prognosis, and prediction of psychotic disorders

Mon, 03 Oct 2022 09:00:59 +0100

Pollak, Thomas A, Rogers, Jonathan P, Nagele, Robert G, Peakman, Mark, Stone, James M, David, Anthony S and McGuire, Philip (2019) Antibodies in the diagnosis, prognosis, and prediction of psychotic disorders. Schizophrenia Bulletin, 45 (1). pp. 233-246. ISSN 0586-7614

Gut feeling: randomized controlled trials of probiotics for the treatment of clinical depression: systematic review and meta-analysis

Mon, 03 Oct 2022 08:56:43 +0100

Nikolova, Viktoriya, Zaidi, Syed Yawar, Young, Allan H, Cleare, Anthony J and Stone, James M (2019) Gut feeling: randomized controlled trials of probiotics for the treatment of clinical depression: systematic review and meta-analysis. Ther Adv Psychopharmacol, 9. a2045125319859963 1-7. ISSN 2045-1253

Basic self-disturbances related to reduced anterior cingulate volume in subjects at ultra-high risk for psychosis

Mon, 03 Oct 2022 08:52:50 +0100

Bonoldi, Ilaria, Allen, Paul, Madeira, Luis, Tognin, Stefania, Bossong, Mattijis G, Azis, Mathilda, Samson, Carly, Quinn, Beverly, Calem, Maria, Valmaggia, Lucia, Modinos, Gemma, Stone, James, Perez, Jesus, Howes, Oliver, Politi, Pierluigi, Kempton, Matthew J, Fusar-Poli, Paolo and McGuire, Philip (2019) Basic self-disturbances related to reduced anterior cingulate volume in subjects at ultra-high risk for psychosis. Frontiers in Psychiatry, 10. a254 1-11. ISSN 1664-0640

The effects of Acute Δ9-tetrahydrocannabinol on striatal glutamatergic function: a proton magnetic resonance spectroscopy study

Tue, 21 Jun 2022 10:13:27 +0100

Bloomfield, Michael A P, Petrilli, Katherine, Lees, Rachel, Hindocha, Chandni, Beck, Katherine, Turner, Ryan J, Onwordi, Ellis Chika, Rane, Neil, Lythgoe, David J, Stone, James M, Curran, H Valerie, Howes, Oliver D and Freeman, Tom P (2021) The effects of Acute Δ9-tetrahydrocannabinol on striatal glutamatergic function: a proton magnetic resonance spectroscopy study. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 6 (6). pp. 660-667. ISSN 2451-9022

Impact of COVID-19 on mental health research: is this the breaking point?

Tue, 21 Jun 2022 10:04:08 +0100

Sparasci, Oli, Bhui, Kamaldeep, Biswas, Asit, Chamberlain, Samuel, Dubicka, Bernadka, Dudas, Robert, Farooq, Saeed, Ford, Tamsin, Husain, Nusrat, Jones, Ian, Killaspy, Helen, Lee, William, Lingford-Hughes, Anne, Mulholland, Ciaran, Stone, James and others, (2022) Impact of COVID-19 on mental health research: is this the breaking point? British Journal of Psychiatry, 220 (5). pp. 1-3. ISSN 0007-1250

Ketamine for depression

Mon, 20 Jun 2022 19:35:55 +0100

Jelen, LA and Stone, James (2021) Ketamine for depression. International Review of Psychiatry, 33 (3). pp. 207-228. ISSN 0954-0261

The prevalence and incidence of Irritable Bowel Syndrome and Inflammatory Bowel Disease in depression and bipolar disorder: a systematic review and meta-analysis

Mon, 20 Jun 2022 19:16:02 +0100

Nikolova, Viktoriya L, Pelton, Lucy, Moulton, Calum D, Zorzato, Daniele, Cleare, Anthony J, Young, Allan H and Stone, James (2022) The prevalence and incidence of Irritable Bowel Syndrome and Inflammatory Bowel Disease in depression and bipolar disorder: a systematic review and meta-analysis. Psychosomatic Medicine, 84 (3). pp. 313-324. ISSN 0033-3174

Brain volume in chronic ketamine users — relationship to sub-threshold psychotic symptoms and relevance to schizophrenia

Mon, 20 Jun 2022 19:02:03 +0100

Chesters, R A, Pepper, F, Morgan, C, Cooper, J D, Howes, O D, Vernon, A C and Stone, James (2021) Brain volume in chronic ketamine users — relationship to sub-threshold psychotic symptoms and relevance to schizophrenia. Psychopharmacology. pp. 1-9. ISSN 0033-3158

Resting-state connectivity studies as a marker of the acute and delayed effects of subanaesthetic ketamine administration in healthy and depressed individuals: a systematic review

Mon, 20 Jun 2022 10:24:12 +0100

Kotoula, Vasileia, Webster, Toby, Stone, James and Mehta, Mitul A (2021) Resting-state connectivity studies as a marker of the acute and delayed effects of subanaesthetic ketamine administration in healthy and depressed individuals: a systematic review. Brain and Neuroscience Advances, 5. p. 23982128211055426. ISSN 2398-2128

Perturbations in gut microbiota composition in psychiatric disorders: a review and meta-analysis

Mon, 20 Jun 2022 08:33:16 +0100

Nikolova, V L, Hall, M R B, Hall, L J, Cleare, A J, Stone, James and Young, A H (2021) Perturbations in gut microbiota composition in psychiatric disorders: a review and meta-analysis. JAMA Psychiatry, 78 (12). pp. 1343-1354. ISSN 2168-622X

GABAA and NMDA receptor density alterations and their behavioral correlates in the gestational methylazoxymethanol acetate model for schizophrenia

Thu, 26 May 2022 12:26:26 +0100

Kiemes, Amanda, Gomes, Felipe V, Cash, Diana, Uliana, Daniela L, Simmons, Camilla, Singh, Nisha, Vernon, Anthony C, Turkheimer, Federico, Davies, Cathy, Stone, James M, Grace, Anthony A and Modinos, Gemma (2022) GABAA and NMDA receptor density alterations and their behavioral correlates in the gestational methylazoxymethanol acetate model for schizophrenia. Neuropsychopharmacology, 47 (3). pp. 687-695. ISSN 0893-133X

Correction: adverse clinical outcomes in people at clinical high-risk for psychosis related to altered interactions between hippocampal activity and glutamatergic function

Fri, 13 May 2022 15:54:31 +0100

Allen, Paul, Hird, Emily J, Orlov, Natasza, Modinos, Gemma, Bossong, Matthijs, Antoniades, Mathilde, Sampson, Carly, Azis, Matilda, Howes, Oliver, Stone, James, Perez, Jesus, Broome, Matthew, Grace, Anthony A and McGuire, Philip (2021) Correction: adverse clinical outcomes in people at clinical high-risk for psychosis related to altered interactions between hippocampal activity and glutamatergic function. Translational Psychiatry, 11. a607 1-1. ISSN 2158-3188

Adverse clinical outcomes in people at clinical high-risk for psychosis related to altered interactions between hippocampal activity and glutamatergic function

Fri, 14 Jan 2022 10:17:59 +0000

Allen, Paul, Hird, Emily J, Orlov, Natasza, Modinos, Gemma, Bossong, Matthijs, Antoniades, Mathilde, Sampson, Carly, Azis, Matilda, Howes, Oliver, Stone, James, Perez, Jesus, Broome, Matthew, Grace, Anthony A and McGuire, Philip (2021) Adverse clinical outcomes in people at clinical high-risk for psychosis related to altered interactions between hippocampal activity and glutamatergic function. Translational Psychiatry, 11 (1). a579 1-9. ISSN 2158-3188

Imaging brain Glx dynamics in response to pressure pain stimulation: a ¹H-fMRS study

Thu, 23 Sep 2021 06:53:58 +0100

Jelen, Luke A, Lythgoe, David J, Jackson, Jade B, Howard, Matthew A, Stone, James M and Egerton, Alice (2021) Imaging brain Glx dynamics in response to pressure pain stimulation: a ¹H-fMRS study. Frontiers in Psychiatry, 12. a681419 1-12. ISSN 1664-0640

N-methyl-D-aspartate receptor availability in first-episode psychosis: a PET-MR brain imaging study

Thu, 23 Sep 2021 06:39:44 +0100

Beck, Katherine, Arumuham, Atheeshaan, Veronese, Mattia, Santangelo, Barbara, McGinnity, Colm J, Dunn, Joel, McCutcheon, Robert A, Kaar, Stephen J, Singh, Nisha, Pillinger, Toby, Borgan, Faith, Stone, James, Jauhar, Sameer, Sementa, Teresa, Turkheimer, Federico, Hammers, Alexander and Howes, Oliver D (2021) N-methyl-D-aspartate receptor availability in first-episode psychosis: a PET-MR brain imaging study. Translational Psychiatry, 11 (1). a425 1-8. ISSN 2158-3188

Association of age, antipsychotic medication, and symptom severity in schizophrenia with proton magnetic resonance spectroscopy brain glutamate level: a mega-analysis of individual participant-level data

Tue, 21 Sep 2021 16:58:19 +0100

Merritt, Kate, McGuire, Philip K, Egerton, Alice, Aleman, André, Block, Wolfgang, Bloemen, Oswald J N, Borgan, Faith, Bustillo, Juan R, Capizzano, Aristides A, Coughlin, Jennifer Marie, De La Fuente-Sandoval, Camilo, Demjaha, Arsime, Dempster, Kara, Do, Kim Q, Stone, James, the 1H-MRS in Schizophrenia Investigators, and others, (2021) Association of age, antipsychotic medication, and symptom severity in schizophrenia with proton magnetic resonance spectroscopy brain glutamate level: a mega-analysis of individual participant-level data. JAMA Psychiatry, 78. pp. 667-681. ISSN 2168-622X

Ketamine: a tale of two enantiomers

Thu, 09 Sep 2021 09:59:48 +0100

Jelen, Luke A, Young, Allan H and Stone, James M (2021) Ketamine: a tale of two enantiomers. Journal of Psychopharmacology, 35 (2). pp. 109-123. ISSN 0269-8811

Interactions between hippocampal activity and striatal dopamine in people at clinical high risk for psychosis: relationship to adverse outcomes

Thu, 09 Sep 2021 08:41:30 +0100

Modinos, Gemma, Richter, Anja, Egerton, Alice, Bonoldi, Ilaria, Azis, Matilda, Antoniades, Mathilde, Bossong, Matthijs, Crossley, Nicolas, Perez, Jesus, Stone, James M, Veronese, Mattia, Zelaya, Fernando, Grace, Anthony A, Howes, Oliver D, Allen, Paul and McGuire, Philip (2021) Interactions between hippocampal activity and striatal dopamine in people at clinical high risk for psychosis: relationship to adverse outcomes. Neuropsychopharmacology, 46. pp. 1468-1474. ISSN 0893-133X

Changes in brain glutamate on switching to clozapine in treatment-resistant schizophrenia

Fri, 20 Aug 2021 14:29:44 +0100

McQueen, Grant, Sendt, Kyra-Verena, Gillespie, Amy, Avila, Alessia, Lally, John, Vallianatou, Kalliopi, Chang, Nynn, Ferreira, Diogo, Borgan, Faith, Howes, Oliver D, Barker, Gareth J, Lythgoe, David J, Stone, James M, McGuire, Philip, MacCabe, James H and Egerton, Alice (2021) Changes in brain glutamate on switching to clozapine in treatment-resistant schizophrenia. Schizophrenia Bulletin, 47 (3). pp. 662-671. ISSN 0586-7614

GABA, glutamate and neural activity: a systematic review with meta-analysis of multimodal ¹H-MRS-fMRI studies

Thu, 03 Jun 2021 12:33:36 +0100

Kiemes, Amanda, Davies, Cathy, Kempton, Matthew J, Lukow, Paulina B, Bennallick, Carly, Stone, James M and Modinos, Gemma (2021) GABA, glutamate and neural activity: a systematic review with meta-analysis of multimodal ¹H-MRS-fMRI studies. Frontiers in Psychiatry, 12. a644315 1-24. ISSN 1664-0640

Updated review and meta-analysis of probiotics for the treatment of clinical depression: adjunctive vs. stand-alone treatment

Thu, 03 Jun 2021 12:25:20 +0100

Nikolova, Viktoriya L, Cleare, Anthony J, Young, Allan H and Stone, James M (2021) Updated review and meta-analysis of probiotics for the treatment of clinical depression: adjunctive vs. stand-alone treatment. Journal of Clinical Medicine, 10 (4). a647 1-14. ISSN 2077-0383