Development of a model for finding unlabeled cases of rheumatoid arthritis in UK primary care patient records

Ford, Elizabeth, Lupton, Grace, Rooney, Philip, Oliver, Seb and Cassell, Jackie (2018) Development of a model for finding unlabeled cases of rheumatoid arthritis in UK primary care patient records. In: Medical Informatics Europe 2018, 24th-26th April 2018, Gothenburg, Sweden. (Accepted)

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Abstract

When using electronic patient records (EPR) from UK primary care for research, it is not possible to tell the difference between “negative” and “positive, but unlabeled” cases. Using the exemplar of rheumatoid arthritis (RA), we developed a logistic regression model which could be used to identify cases of RA which are unlabeled. Combining symptom, referral and test information from codes and free text, our model discriminated between RA cases and controls with an AUROC of 0.923. This method for identifying “positive, unlabeled” cases in patient records has the potential to improve case ascertainment for a range of EPR studies.

Item Type: Conference or Workshop Item (Paper)
Keywords: Patient records, primary care, rheumatoid arthritis, data quality
Schools and Departments: Brighton and Sussex Medical School > Primary Care and Public Health
School of Mathematical and Physical Sciences > Physics and Astronomy
Research Centres and Groups: Astronomy Centre
Subjects: R Medicine > R Medicine (General) > R858 Computer applications to medicine. Medical informatics
Depositing User: Elizabeth Ford
Date Deposited: 26 Mar 2018 15:59
Last Modified: 01 May 2018 14:29
URI: http://sro.sussex.ac.uk/id/eprint/74659

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Project NameSussex Project NumberFunderFunder Ref
The ergonomics of electric patient records: an interdisciplinary development of methodologies for understanding and exploiting free text to enhance the utility of primary care electronic patient recordsG0011WELLCOME TRUST086105/Z/08/Z