Predictors of death after Clostridium difficile infection: a report on 128 strain-typed cases from a teaching hospital in the United Kingdom

Wilson, Vhairi, Cheek, Liz, Satta, Giovanni, Walker-Bone, Karen, Cubbon, Marc, Citron, Diane, Gerding, Dale N and Llewelyn, Martin J. (2010) Predictors of death after Clostridium difficile infection: a report on 128 strain-typed cases from a teaching hospital in the United Kingdom. Clinical Infectious Diseases, 50 (12). e77-e81. ISSN 1058-4838

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Abstract

We assessed the relationship between strain type, clinical factors, and outcome in 128 patients with Clostridium difficile infection. Strain type was not associated with any outcome measure. On multivariate analysis, ischemic heart disease and hypoalbuminemia predicted death. Metronidazole treatment in severe disease was associated with a higher rate of treatment failure and death.

Item Type: Article
Additional Information: IDS Number: 598BF
Keywords: DIARRHEA; METRONIDAZOLE; MORTALITY; SEVERITY; EPIDEMIC; DISEASE
Schools and Departments: School of History, Art History and Philosophy > History
Subjects: Q Science > QR Microbiology > QR0180 Immunology
R Medicine > RC Internal medicine
R Medicine > RC Internal medicine > RC0109 Infectious and parasitic diseases
Depositing User: Tracey O'Gorman
Date Deposited: 24 Aug 2011 13:22
Last Modified: 15 Dec 2014 12:20
URI: http://sro.sussex.ac.uk/id/eprint/7150
Google Scholar:6 Citations
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