Bridging the age gap in breast cancer: evaluation of decision support interventions for older women with operable breast cancer: protocol for a cluster randomised controlled trial

Collins, Karen, Reed, Malcolm, Lifford, Kate, Burton, Maria, Edwards, Adrian, Ring, Alistair, Brain, Katherine, Harder, Helena, Robinson, Thompson, Cheung, Kwok Leung and et al, (2017) Bridging the age gap in breast cancer: evaluation of decision support interventions for older women with operable breast cancer: protocol for a cluster randomised controlled trial. British Medical Journal, 7 (7). e015133. ISSN 0959-8138

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Abstract

Whilst breast cancer outcomes are improving steadily in younger women due to advances in screening and improved therapies, there has been little change in outcomes among the older age group. It is inevitable that co-morbidities/frailty rates are higher, which may increase the risks of some breast cancer treatments such as surgery and chemotherapy, many older women are healthy and may benefit from their use. Adjusting treatment regimens appropriately for age/co-morbidity/frailty is variable and largely non-evidence based, specifically with regard to rates of surgery for operable oestrogen receptor (ER) positive disease and rates of chemotherapy for high-risk disease.

Item Type: Article
Schools and Departments: Brighton and Sussex Medical School > Brighton and Sussex Medical School
Brighton and Sussex Medical School > Sussex Health Outcomes Research & Education in Cancer (SHORE-C)
Subjects: R Medicine > RD Surgery > RD0651 Neoplasms. Tumors. Oncology
Depositing User: Esme Acton-Stewart
Date Deposited: 22 Jun 2017 12:59
Last Modified: 09 Nov 2017 18:06
URI: http://sro.sussex.ac.uk/id/eprint/68596

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