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Advances in pharmaceutical development of modified-release drug formulations and products

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posted on 2023-06-09, 05:51 authored by Mohammed Maniruzzaman, Ali Nokhodchi
The ongoing need to provide greater therapeutic efficacy and reduced side effects has accelerated the interest in modified-release oral dosage formulations. Orally-taken solid dosage forms continue to play a central role in the treatment of various medical conditions. Modified-release formulations are one of the most common systems for oral delivery due to improved compliance and reduction in the frequency of dosing. Based on the needs and challenges of modified-release formulations, a variety of novel modified-release platforms have been developed. This review aims to enhance the knowledge and understanding of properties of modified-release formulations and explains how these products release their active ingredients. The review also emphasises the types of modified-release dosage forms with reference to the commercial excipients and polymers currently used during the formulation development.

History

Publication status

  • Published

File Version

  • Accepted version

Journal

Nurse Prescribing

ISSN

1479-9189

Publisher

Mark Allen Healthcare

Issue

5

Volume

15

Page range

246-252

Department affiliated with

  • Chemistry Publications

Full text available

  • Yes

Peer reviewed?

  • Yes

Legacy Posted Date

2017-04-20

First Open Access (FOA) Date

2017-05-15

First Compliant Deposit (FCD) Date

2017-04-20

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