A copper-benzotriazole based coordination polymer catalyzes the efficient one-pot synthesis of (N'-substituted)-hydrazo-4-aryl-1,4-dihydropyridines from azines

Kallitsakis, Michael, Loukopoulos, Edward, Abdul-Sada, Alaa, Tizzard, Graham J, Coles, Simon J, Kostakis, George E and Lykakis, Ioannis N (2017) A copper-benzotriazole based coordination polymer catalyzes the efficient one-pot synthesis of (N'-substituted)-hydrazo-4-aryl-1,4-dihydropyridines from azines. Advanced Synthesis and Catalysis, 359 (1). pp. 138-145. ISSN 1615-4150

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Abstract

A series of new (N’-substituted)-hydrazo-4-aryl-1,4 dihydropyridines were successfully synthesized via a facile one pot catalytic pathway utilizing azines and propiolate esters as starting materials and 1D Cu benzotriazoles based coordination polymer as catalyst. In the absence of catalyst, the corresponding 5-substituted 4,5-dihydro pyrazoles were formed in moderate to high yields. Fine-tuning the catalysts allowed us to gain more insights regarding the plausible reaction mechanism.

Item Type: Article
Keywords: 1,4-dihydropyridines,Copper,Homogeneous catalysis,azines,coordination polymer
Schools and Departments: School of Life Sciences > Chemistry
Subjects: Q Science > QD Chemistry > QD0146 Inorganic chemistry
Depositing User: Georgios Kostakis
Date Deposited: 12 Oct 2016 13:42
Last Modified: 08 Mar 2017 08:50
URI: http://sro.sussex.ac.uk/id/eprint/64724

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