Human leukocyte antigen class II haplotypes that protect against or predispose to streptococcal toxic shock

Llewelyn, Martin (2005) Human leukocyte antigen class II haplotypes that protect against or predispose to streptococcal toxic shock. Clinical Infectious Diseases, 41 (Sup 7). S445-S448. ISSN 1537-6591

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Abstract

In the United States, 1.5-5.2/100,000 persons develop invasive Streptococcus pyogenes infections each year, and approximately 10%-20% of these patients go on to develop streptococcal toxic shock syndrome (STSS). Patients who develop STSS usually present with generalized erythema, conjunctivitis, and confusion. Fulminant cardiovascular shock develops over a period of a few hours, accompanied by multiorgan failure. Between 20% and 40% of patients with STSS die, compared with approximately 10% of patients with invasive streptococcal disease without STSS.

Item Type: Article
Schools and Departments: Brighton and Sussex Medical School > Brighton and Sussex Medical School
Depositing User: Sandy Gray
Date Deposited: 14 Sep 2016 13:45
Last Modified: 22 Sep 2016 15:05
URI: http://sro.sussex.ac.uk/id/eprint/63328
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