A conserved trans-regulatory landscape for scute expression on the notum of cyclorraphous Diptera

Richardson, Joanna and Simpson, Pat (2006) A conserved trans-regulatory landscape for scute expression on the notum of cyclorraphous Diptera. Development Genes and Evolution, 216 (1). pp. 29-38. ISSN 0949-944X

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Abstract

Bristles on the notum of many cyclorraphous flies are arranged into species-specific stereotyped patterns. The positions of bristles correlate with differences in the spatial expression of the scute (sc) gene in those species examined so far. However, a major upstream activator of scute, Pannier (Pnr), is expressed in a conserved domain over the entire medial notum. Here we examine the expression patterns in Calliphora vicina of stripe (sr), u-shaped (ush), caupolican (caup) and wingless (wg), genes known to modify the activity of Pnr or to act downstream of Pnr in Drosophila. We find that, with minor differences, their expression patterns are conserved. This suggests that the function of a trans-regulatory network of genes is relatively unchanged in derived Diptera and that many differences are likely to be due to changes in cis-regulatory sequences of scute.

Item Type: Article
Keywords: Calliphora, Cyclorraphous flies, Bristle pattern, Notum
Schools and Departments: School of Life Sciences > Biochemistry
Subjects: Q Science > QH Natural history > QH0301 Biology > QH0426 Genetics
Q Science > QL Zoology > QL0799 Morphology
Q Science > QL Zoology > QL0951 Embryology
Depositing User: Joanna Richardson
Date Deposited: 28 Jul 2016 08:41
Last Modified: 08 Mar 2017 05:06
URI: http://sro.sussex.ac.uk/id/eprint/62133

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