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Thinking Well: a randomised controlled feasibility study of a new CBT therapy targeting reasoning biases in people with distressing persecutory delusional beliefs
journal contribution
posted on 2023-06-09, 02:15 authored by Helen Waller, Richard Emsley, Daniel Freeman, Paul Bebbington, Graham Dunn, David FowlerDavid Fowler, Amy Hardy, Elizabeth Kuipers, Philippa GaretyBackground and objectives Delusional beliefs with persecutory content are common in psychosis, but difficult to treat. Interventions targeting hypothesised causal and maintaining factors have been proposed as a way of improving therapy. The current study is a feasibility randomised controlled trial of the ‘Thinking Well (TW)’ intervention: This novel approach combines the recently developed Maudsley Review Training Programme (MRTP), with additional, focussed cognitive-behavioural therapy sessions. Methods 31 participants with distressing persecutory delusions and schizophrenia spectrum disorders were randomised to TW or to treatment as usual in a 2:1 ratio. Participants completed outcome assessments at 0 (baseline), 1 (post-MRTP), 6 (post-TW) and 8 (follow-up) weeks. Key outcomes included belief flexibility, paranoia, and delusional conviction and distress. Participants allocated to TW completed the MRTP package and four CBT sessions with a clinical psychologist. Results Recruitment proved feasible. Participants reported the intervention was relevant and had resulted in positive changes in thinking and mood, which they could use in everyday life. Treatment effects were moderate-large for key outcomes including belief flexibility, paranoia conviction and distress. The additional TW sessions appeared to confer benefits over MRTP alone. Limitations Assessments were not carried out blind to treatment condition. Recruitment was opportunistic, from an identified pool of research participants. Finally, a few participants had already completed the MRTP as part of a previous study. Conclusions The TW intervention appears to be feasible and acceptable to participants, and the effects of treatment are promising. A fully powered randomised controlled trial of the intervention is warranted.
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Publication status
- Published
File Version
- Published version
Journal
Journal of Behavior Therapy and Experimental PsychiatryISSN
0005-7916Publisher
ElsevierExternal DOI
Volume
48Page range
82-89Department affiliated with
- Psychology Publications
Full text available
- Yes
Peer reviewed?
- Yes
Legacy Posted Date
2016-07-26First Open Access (FOA) Date
2016-07-26First Compliant Deposit (FCD) Date
2016-07-26Usage metrics
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