The people with Asperger Syndrome and anxiety disorders (PAsSA) trial: a pilot multi-centre single blind randomised trial of group cognitive behavioural therapy

Fowler, David, Langdon, Peter E, Murphy, Glynis H, Shepstone, Lee, Wilson, Edward E, Heavens, David, Malovic, Aida, Russell, Alexandra, Rose, Alice and Mullineaux, Louise (2016) The people with Asperger Syndrome and anxiety disorders (PAsSA) trial: a pilot multi-centre single blind randomised trial of group cognitive behavioural therapy. British Journal of Psychiatry, 2 (2). pp. 179-186. ISSN 0007-1250

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Abstract

Background: There is a growing interest in using cognitive behavioural therapy (CBT) with people who have Asperger Syndrome (AS) and comorbid mental health problems.

Aims: To examine whether modified group CBT for clinically significant anxiety in an AS population is feasible and likely to be efficacious.

Method: Using a randomised assessor-blind trial, 52 individuals with AS were randomised into a treatment arm or a waiting-list control arm. After 24 weeks, those in the waiting-list control arm received treatment, while those initially randomised to treatment were followed-up for 24 weeks.

Results: The conversion rate for this trial was high (1.6:1), while attrition was 13%. After 24 weeks, there was no significant difference between those randomised to the treatment arm compared to those randomised to the waiting-list control arm on the primary outcome measure, the Hamilton Rating Scale for Anxiety.

Conclusions: Trials of psychological therapies with this population are feasible. Larger definitive trials are now needed.
Declaration of Interest: None

Trial Registration: ISRCTN 30265294 (DOI: 10.1186/ISRCTN30265294), UKCRN 8370

Item Type: Article
Schools and Departments: School of Psychology > Psychology
Depositing User: David Fowler
Date Deposited: 30 Mar 2016 07:31
Last Modified: 02 Apr 2017 13:13
URI: http://sro.sussex.ac.uk/id/eprint/60142

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