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Strategies in functional proteomics: unveiling the pathways to precision oncology
journal contribution
posted on 2023-06-09, 00:22 authored by Rosy Favicchio, Chloe Thepaut, Hua Zhang, Richard Arends, Justin Stebbing, Georgios GiamasGeorgios GiamasPersonalised strategies in cancer care are required to overcome the therapeutic challenges posed by variability between patients and disease subsets. To this end, enhanced precision tools must be developed to describe the molecular drivers of malignant proliferation. Such tools must also identify druggable targets and biomarkers in order to provide essential information regarding drug development and therapeutic outcome. Here we discuss how proteomics-based approaches provide a set of viable methodologies capable of delivering quantitative information throughout the main stages of personalised oncology and a ratiometric platform that delivers systems-wide methods for drug evaluation.
History
Publication status
- Published
Journal
Cancer LettersISSN
0304-3835Publisher
ElsevierExternal DOI
Issue
1Volume
382Page range
86-94Department affiliated with
- Biochemistry Publications
Full text available
- No
Peer reviewed?
- Yes
Legacy Posted Date
2016-02-23Usage metrics
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