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Strategies in functional proteomics: unveiling the pathways to precision oncology

journal contribution
posted on 2023-06-09, 00:22 authored by Rosy Favicchio, Chloe Thepaut, Hua Zhang, Richard Arends, Justin Stebbing, Georgios GiamasGeorgios Giamas
Personalised strategies in cancer care are required to overcome the therapeutic challenges posed by variability between patients and disease subsets. To this end, enhanced precision tools must be developed to describe the molecular drivers of malignant proliferation. Such tools must also identify druggable targets and biomarkers in order to provide essential information regarding drug development and therapeutic outcome. Here we discuss how proteomics-based approaches provide a set of viable methodologies capable of delivering quantitative information throughout the main stages of personalised oncology and a ratiometric platform that delivers systems-wide methods for drug evaluation.

History

Publication status

  • Published

Journal

Cancer Letters

ISSN

0304-3835

Publisher

Elsevier

Issue

1

Volume

382

Page range

86-94

Department affiliated with

  • Biochemistry Publications

Full text available

  • No

Peer reviewed?

  • Yes

Legacy Posted Date

2016-02-23

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