Monitoring changes of paramagnetically-shifted 31P signals in phospholipid vesicles

Joyce, Rebecca E, Williams, Thomas L, Serpell, Louise C and Day, Iain J (2016) Monitoring changes of paramagnetically-shifted 31P signals in phospholipid vesicles. Chemical Physics Letters. ISSN 0009-2614

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Abstract

Phospholipid vesicles are commonly used as biomimetics in the investigation of the interaction of various species with cell membranes. In this paper we present a 31P NMR investigation of a simple vesicle system using a paramagnetic shift reagent to probe the inner and outer layers of the lipid bilayer. Time-dependent changes in the 31P NMR signal are observed, which differ whether the paramagnetic species is inside or outside the vesicle, and on the choice of buffer solution used. An interpretation of these results is given in terms of the interaction of the paramagnetic shift reagent with the lipids.

Item Type: Article
Schools and Departments: School of Life Sciences > Chemistry
Subjects: Q Science > QD Chemistry > QD0450 Physical and theoretical chemistry
Depositing User: Iain Day
Date Deposited: 09 Feb 2016 12:00
Last Modified: 24 Mar 2017 12:48
URI: http://sro.sussex.ac.uk/id/eprint/59592

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