Mesoporous silica nanoparticles in nanotechnology

Douroumis, Dennis, Onyesom, Ichioma, Maniruzzaman, Mohammed and Mitchell, John (2013) Mesoporous silica nanoparticles in nanotechnology. Critical Reviews in Biotechnology, 33 (3). pp. 229-245. ISSN 0738-8551

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Abstract

Mesoporous silica nanoparticles (MSNs) are a versatile drug delivery system that can be used for loading of different guest molecules such as peptides, proteins, anticancer agents, and genetic material. MSNs are considered promising drug carriers due to their tuneable particle size, pore structure, and surface functionalization. Thus, MSNs provide opportunities for their effective application in a wide variety of fields. In the current review, we discuss both conventional and advanced MSNs synthesis methods, including their applications for drug delivery, gatekeepers, and biosensors. In addition, the research progress in biocompatibility, cytotoxicity, and internalization mechanisms is reported.

Item Type: Article
Schools and Departments: School of Life Sciences > Chemistry
Depositing User: Mohammed Maniruzzaman
Date Deposited: 29 Jan 2016 11:20
Last Modified: 29 Jan 2016 11:20
URI: http://sro.sussex.ac.uk/id/eprint/59489
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