A novel non-invasive sensor based on electric field detection for cardio-electrophysiology in zebrafish embryos

Rendon-Morales, Elizabeth, Prance, Helen, Prance, Robert and Aviles-Espinosa, Rodrigo (2016) A novel non-invasive sensor based on electric field detection for cardio-electrophysiology in zebrafish embryos. In: Biosensors Congres Elsevier 2016, 25-27 May 2016, Gothenburg, Sweden. (Accepted)

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Abstract

Currently, there is no effective sensing technology available to monitor the electrocardiogram activity of the living zebrafish heart during early developmental stages. Most of the methods are based either on the use of simple visual inspections which are limited to quantifying the heart rate or invasive methodologies which require the insertion of electrodes or heart explantation techniques both requiring the use of expensive differential amplifiers and noise isolated environments. In this paper we report the continuous detection of the cardiac electrical activity in embryonic zebrafish using a non-invasive approach. We present a portable and cost-effective platform based on the Electric Potential Sensing technology, to monitor in vivo electrocardiogram activity from the zebrafish heart. This proof of principle demonstration shows how electrocardiogram measurements from embryonic zebrafish may become accessible by using the electric field detection method. We present results obtained using the experimental prototype, which enables the acquisition of cardio-electrophysiological signals from in vivo zebrafish embryos.

Item Type: Conference or Workshop Item (Poster)
Keywords: Biosensors, Electric Potential Sensor, electrophysiology, embryo heart.
Schools and Departments: School of Engineering and Informatics > Informatics
Subjects: T Technology > TA Engineering (General). Civil engineering (General) > TA0164 Bioengineering
T Technology > TA Engineering (General). Civil engineering (General) > TA0174 Engineering design
T Technology > TK Electrical engineering. Electronics Nuclear engineering > TK0275 Electric standards and measurements
T Technology > TK Electrical engineering. Electronics Nuclear engineering > TK0301 Electric meters
T Technology > TK Electrical engineering. Electronics Nuclear engineering > TK0452 Electric apparatus and materials. Electric circuits. Electric networks
Depositing User: Elizabeth Rendon Morales
Date Deposited: 22 Feb 2016 12:41
Last Modified: 22 Feb 2016 12:41
URI: http://sro.sussex.ac.uk/id/eprint/59464
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