Non-invasive electrocardiogram detection of in vivo zebrafish embryos using electric potential sensors

Rendon-Morales, Elizabeth, Prance, Robert, Prance, Helen and Aviles-Espinosa, Rodrigo (2015) Non-invasive electrocardiogram detection of in vivo zebrafish embryos using electric potential sensors. Applied Physics Letters, 107 (19). 193701-1-193701-4. ISSN 0003-6951

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Abstract

In this Letter we report the continuous detection of the cardiac electrical activity in embryonic zebrafish using a non-invasive approach. We present a portable and cost-effective platform based on the Electric Potential Sensing technology, to monitor in vivo electrocardiogram activity from the zebrafish heart. This proof of principle demonstration shows how electrocardiogram measurements from embryonic zebrafish may become accessible by using electric field detection. We present preliminary results using the prototype, which enables the acquisition of electrophysiological signals from in vivo 3 and 5 days-post-fertilization zebrafish embryos. The recorded waveforms show electrocardiogram traces including detailed features such as QRS complex, P and T waves.

Item Type: Article
Keywords: electrocardiogram, electric field, electric potential sensors, cardiovascular electronics
Schools and Departments: School of Engineering and Informatics > Informatics
Subjects: T Technology
T Technology > TK Electrical engineering. Electronics Nuclear engineering
T Technology > TK Electrical engineering. Electronics Nuclear engineering > TK0301 Electric meters
T Technology > TK Electrical engineering. Electronics Nuclear engineering > TK0452 Electric apparatus and materials. Electric circuits. Electric networks
T Technology > TK Electrical engineering. Electronics Nuclear engineering > TK7800 Electronics
Depositing User: Elizabeth Rendon Morales
Date Deposited: 28 Oct 2015 15:34
Last Modified: 26 Sep 2016 10:45
URI: http://sro.sussex.ac.uk/id/eprint/57386
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