Opiate versus psychostimulant addiction: the differences do matter

Badiani, Aldo, Belin, David, Epstein, David, Calu, Donna and Shaham, Yavin (2011) Opiate versus psychostimulant addiction: the differences do matter. Nature reviews. Neuroscience, 12 (11). pp. 685-700. ISSN 1471-003X

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Abstract

The publication of the psychomotor stimulant theory of addiction in 1987 and the finding that addictive drugs increase dopamine concentrations in the rat mesolimbic system in 1988 have led to a predominance of psychobiological theories that consider addiction to opiates and addiction to psychostimulants as essentially identical phenomena. Indeed, current theories of addiction - hedonic allostasis, incentive sensitization, aberrant learning and frontostriatal dysfunction - all argue for a unitary account of drug addiction. This view is challenged by behavioural, cognitive and neurobiological findings in laboratory animals and humans. Here, we argue that opiate addiction and psychostimulant addiction are behaviourally and neurobiologically distinct and that the differences have important implications for addiction treatment, addiction theories and future research.

Item Type: Article
Schools and Departments: School of Psychology > Psychology
Subjects: B Philosophy. Psychology. Religion
Depositing User: Lene Hyltoft
Date Deposited: 28 Oct 2015 12:05
Last Modified: 08 Mar 2017 06:06
URI: http://sro.sussex.ac.uk/id/eprint/57369

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