Memories are made of this: synergy of T cell receptor and cytokine signals in CD4(+) central memory cell survival

Caserta, Stefano and Zamoyska, Rose (2007) Memories are made of this: synergy of T cell receptor and cytokine signals in CD4(+) central memory cell survival. Trends in Immunology, 28 (6). pp. 245-248. ISSN 1471-4906

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Abstract

The ability of the immune system to 'remember' a previous encounter with antigen is the hallmark of the adaptive immune response. The signals required for CD4(+) memory T cell survival are not well understood, and a recent paper lends new biochemical insights into how memory T cells might optimally be preserved through the convergence of signals from the engagement of cytokine and antigen-specific T cell receptors.

Item Type: Article
Keywords: memory T cells
Schools and Departments: Brighton and Sussex Medical School > Clinical and Experimental Medicine
Brighton and Sussex Medical School > Global Health and Infection
Subjects: Q Science > QR Microbiology > QR0180 Immunology
Depositing User: Stefano Caserta
Date Deposited: 30 Sep 2015 07:03
Last Modified: 21 Sep 2017 13:56
URI: http://sro.sussex.ac.uk/id/eprint/56880
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