Social and emotional functions in three patients with medial frontal lobe damage including the anterior cingulate cortex

Baird, Amee, Dewar, Bonnie‐Kate, Critchley, Hugo, Dolan, Ray, Shallice, Tim and Cipolotti, Lisa (2006) Social and emotional functions in three patients with medial frontal lobe damage including the anterior cingulate cortex. Cognitive Neuropsychiatry, 11 (4). pp. 369-388. ISSN 1354-6805

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Abstract

Introduction. The aim of this study was to explore social and emotional functions in patients with medial frontal damage including the anterior cingulate cortex (ACC).

Methods. Three patients with medial frontal lobe lesions primarily involving the ACC performed tasks on motivational decision making, emotional facial expression recognition, and social cognition, including theory of mind (ToM). Their performance on these tasks was compared with age and education matched healthy controls.

Results. Patient performance on the motivational decision making and social situations tasks did not differ from controls. Selective emotional facial expression recognition impairment for fear was evident in one patient with a unilateral right ACC lesion (patient 3). ToM impairment was present in only one patient with a bilateral ACC lesion (patient 2). In contrast, the two patients with unilateral right ACC lesions had intact ToM (patients 1 and 3).

Conclusions. These findings suggest that medial frontal lobe lesions primarily involving the ACC do not appear to critically disrupt motivational decision making or social situation processing. The ACC plays a role in processing particular types of emotion (fear). Bilateral ACC damage impairs ToM processing, but unilateral damage to the right ACC is not sufficient to disrupt ToM.

Item Type: Article
Schools and Departments: Brighton and Sussex Medical School > Brighton and Sussex Medical School
Brighton and Sussex Medical School > Neuroscience
Subjects: R Medicine > RC Internal medicine > RC0321 Neurosciences. Biological psychiatry. Neuropsychiatry
Depositing User: Christina Lee
Date Deposited: 06 Aug 2015 13:43
Last Modified: 26 Sep 2017 11:15
URI: http://sro.sussex.ac.uk/id/eprint/56013

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