File(s) not publicly available
Aryloxypyrazines as highly selective antagonists of Oxytocin
journal contribution
posted on 2023-06-08, 20:55 authored by Alan Brown, Dave Ellis, David Pearce, Michael Ralph, Nunzio SciammettaA series of aryloxypyrazines were designed based on structural overlap with previously reported arylpyrazine Oxytocin antagonists. Similarly high levels of Oxytocin antagonism were achievable in this new series. In addition, significant improvements in selectivity over the related vasopressin V1A receptor were also possible.
History
Publication status
- Published
Journal
Bioorganic and Medicinal Chemistry LettersISSN
0960-894XPublisher
ElsevierExternal DOI
Issue
10Volume
19Page range
2634-2636Department affiliated with
- Chemistry Publications
Full text available
- No
Peer reviewed?
- Yes
Legacy Posted Date
2015-06-01Usage metrics
Categories
No categories selectedKeywords
Licence
Exports
RefWorks
BibTeX
Ref. manager
Endnote
DataCite
NLM
DC