Preparation of tricyclic compounds as CFTR channel inhibitors for treating polycystic kidney disease and diarrhea

Novartis Ag (2014) Preparation of tricyclic compounds as CFTR channel inhibitors for treating polycystic kidney disease and diarrhea. WO2014097147A1.

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Abstract

The present invention provides a CFTR inhibitor of formula (I) or a pharmaceutically acceptable salt thereof; and its therapeutic uses, e.g. in the treatment of diarrhea. The present invention further provides a combination of pharmacological active agents and a pharmaceutical composition.

Item Type: Patent
Schools and Departments: School of Life Sciences > Chemistry
Subjects: Q Science > QD Chemistry
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Depositing User: Tom Gittoes
Date Deposited: 01 Jun 2015 12:49
Last Modified: 01 Jun 2015 12:49
URI: http://sro.sussex.ac.uk/id/eprint/54115
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