Coping with persistent pain, effectiveness research into self-management (COPERS): statistical analysis plan for a randomised controlled trial

Kahan, Brennan C, Diaz-Ordaz, Karla, Homer, Kate, Carnes, Dawn, Underwood, Martin, Taylor, Stephanie J C, Bremner, Stephen and Eldridge, Sandra (2014) Coping with persistent pain, effectiveness research into self-management (COPERS): statistical analysis plan for a randomised controlled trial. Trials, 15 (1). p. 59. ISSN 17456215

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Abstract

Background: The Coping with Persistent Pain, Effectiveness Research into Self-management (COPERS) trial assessed whether a group-based self-management course is effective in reducing pain-related disability in participants with chronic musculoskeletal pain. This article describes the statistical analysis plan for the COPERS trial. Methods and design: COPERS was a pragmatic, multicentre, unmasked, parallel group, randomised controlled trial.
This article describes (a) the overall analysis principles (including which participants will be included in each analysis, how results will be presented, which covariates will be adjusted for, and how we will account for clustering in the intervention group); (b) the primary and secondary outcomes, and how each outcome will be analysed; (c) sensitivity analyses; (d) subgroup analyses; and (e) adherence-adjusted analyses.

Item Type: Article
Additional Information: Trial registration: ISRCTN24426731
Keywords: Statistical analysis plan; Randomised controlled trial; Self-management; Chronic musculoskeletal pain; Complex intervention
Schools and Departments: Brighton and Sussex Medical School > Brighton and Sussex Medical School
Brighton and Sussex Medical School > Primary Care and Public Health
Subjects: R Medicine > RA Public aspects of medicine > RA0001 Medicine and the state. Including medical statistics, medical economics, provisions for medical care, medical sociology > RA0411 Provisions for personal medical care. Medical care plans
R Medicine > RA Public aspects of medicine > RA0001 Medicine and the state. Including medical statistics, medical economics, provisions for medical care, medical sociology > RA0411 Provisions for personal medical care. Medical care plans
Depositing User: Jane Hale
Date Deposited: 30 Apr 2015 15:14
Last Modified: 06 Mar 2017 17:33
URI: http://sro.sussex.ac.uk/id/eprint/53842

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