Keratoprostheses for corneal blindness: a review of contemporary devices

Avadhanam, Venkata, Smith, Helen and Liu, Christopher (2015) Keratoprostheses for corneal blindness: a review of contemporary devices. Clinical Ophthalmology, 9. pp. 697-720. ISSN 1177-5483

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Abstract

According to the World Health Organization, globally 4.9 million are blind due to corneal pathology. Corneal transplantation is successful and curative of the blindness for a majority of these cases. However, it is less successful in a number of diseases that produce corneal neovascularization, dry ocular surface and recurrent inflammation, or infections. A keratoprosthesis or KPro is the only alternative to restore vision when corneal graft is a doomed failure. Although a number of KPros have been proposed, only two devices, Boston type-1 KPro and osteo-odonto-KPro, have came to the fore. The former is totally synthetic and the latter is semi-biological in constitution. These two KPros have different surgical techniques and indications. Keratoprosthetic surgery is complex and should only be undertaken in specialized centers, where expertise, multidisciplinary teams, and resources are available. In this article, we briefly discuss some of the prominent historical KPros and contemporary devices.

Item Type: Article
Keywords: keratoprosthesis, OOKP, KPro, Boston KPro, cornea, ocular surface
Schools and Departments: Brighton and Sussex Medical School > Brighton and Sussex Medical School
Brighton and Sussex Medical School > Primary Care and Public Health
Subjects: R Medicine > RE Ophthalmology
Depositing User: Jane Hale
Date Deposited: 24 Apr 2015 09:32
Last Modified: 06 Mar 2017 15:17
URI: http://sro.sussex.ac.uk/id/eprint/53740

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