Long-term follow-up of placental transfusion in full-term infants

Rabe, Heike, Mercer, Judith S and Erickson-Ownes, Deborah A (2015) Long-term follow-up of placental transfusion in full-term infants. JAMA Pediatrics, 169 (7). ISSN 2168-6203

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Abstract

The effects of redistributing placental blood into healthy full-term newborns at birth by delayed umbilical cord clamping (CC) have been demonstrated in many studies.1 The short-term benefits include higher hemoglobin concentration after birth and increased iron stores until 6 months of age. Early clamping of the cord was introduced in the past to avoid maternal hemorrhage without considering potential neonatal adverse effects. A meta-analysis by McDonald et al1 found no significant differences in postpartum hemorrhage rates when comparing early vs late CC groups in 5 trials that included 2260 women. When that Cochrane review was published, only 1 clinical trial had reported any data on long-term neurodevelopmental outcomes of full-term newborns. Previously, Andersson and colleagues2 reported the outcomes of 4-month-old infants who were randomized to early vs late CC. They did not report any significant difference in scores using the Ages and Stages Questionnaire.

Item Type: Article
Schools and Departments: Brighton and Sussex Medical School > Clinical and Experimental Medicine
Subjects: R Medicine > RJ Pediatrics > RJ0251 Newborn infants Including physiology, care, treatment, diseases
Depositing User: Judy Keogh
Date Deposited: 16 Apr 2015 08:47
Last Modified: 29 Sep 2017 10:08
URI: http://sro.sussex.ac.uk/id/eprint/53671

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