ST13 polymorphisms and their effect on exacerbations in steroid-treated asthmatic children and young adults

Vijverberg, Susanne J, Koster, Ellen S, Tavendale, Roger, Leusink, Maarten, Koenderman, Leo, Raaijmakers, Jan A M, Postma, Dirkje S, Koppelman, Gerard H, Turner, Steve W, Mukhopadhyay, Somnath, Tse, Sze Man, Tantisira, Kelan G, Hawcutt, Daniel B, Francis, Ben, Pirmohamed, Munir, Pino-Yanes, Mario, Eng, Celeste, Burchard, Esteban G, Palmer, Colin N A and Maitland-van der Zee, Anke H (2015) ST13 polymorphisms and their effect on exacerbations in steroid-treated asthmatic children and young adults. Clinical and Experimental Allergy, 45 (6). pp. 1051-1059. ISSN 0954-7894

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Abstract

The clinical response to inhaled corticosteroids (ICS) is associated with single nucleotide polymorphisms (SNPs) in various genes. This study aimed to relate variations in genes in the steroid pathway and asthma susceptibility genes to exacerbations in children and young adults treated with ICS.

Item Type: Article
Keywords: Childhood asthma; Corticosteroids; Exacerbations; Pharmacogenomics; ST13
Schools and Departments: Brighton and Sussex Medical School > Brighton and Sussex Medical School
Subjects: R Medicine > RJ Pediatrics > RJ0047.3 Genetic aspects
R Medicine > RJ Pediatrics > RJ0101 Child health. Child health services
Depositing User: Judy Keogh
Date Deposited: 23 Mar 2015 13:11
Last Modified: 22 Sep 2015 12:29
URI: http://sro.sussex.ac.uk/id/eprint/53483
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