Superficial amygdala and hippocampal activity during affective music listening observed at 3 T but not 1.5 T fMRI

Skouras, Stavros, Gray, Marcus, Critchley, Hugo and Koelsch, Stefan (2014) Superficial amygdala and hippocampal activity during affective music listening observed at 3 T but not 1.5 T fMRI. NeuroImage, 101. pp. 364-369. ISSN 10538119

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Abstract

The purpose of this study was to compare 3 T and 1.5 T fMRI results during emotional music listening. Stimuli comprised of psychoacoustically balanced instrumental musical pieces, with three different affective expressions (fear, neutral, joy). Participants (N = 32) were split into two groups, one subjected to fMRI scanning using 3 T and another group scanned using 1.5 T. Whole brain t-tests (corrected for multiple comparisons) compared joy and fear in each of the two groups. The 3 T group showed significant activity differences between joy and fear localized in bilateral superficial amygdala, bilateral hippocampus and bilateral auditory cortex. The 1.5 T group showed significant activity differences between joy and fear localized in bilateral auditory cortex and cuneus. This is the first study to compare results obtained under different field strengths with regard to affective processes elicited by means of auditory/musical stimulation. The findings raise concern over false negatives in the superficial amygdala and hippocampus in affective studies conducted under 1.5 T and caution that imaging improvements due to increasing magnetic field strength can be influenced by region-specific characteristics.

Item Type: Article
Keywords: 3 T; 1.5 T; Amygdala; Hippocampus; Cuneus; Auditory; Emotion; Joy; Fear; Music
Schools and Departments: School of Psychology > Psychology
Brighton and Sussex Medical School > Neuroscience
Subjects: R Medicine > RC Internal medicine > RC0321 Neurosciences. Biological psychiatry. Neuropsychiatry
Depositing User: Christina Lee
Date Deposited: 08 Mar 2015 10:34
Last Modified: 28 Jul 2017 19:12
URI: http://sro.sussex.ac.uk/id/eprint/53262

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