Diabetes dietary management alters responses to food pictures in brain regions associated with motivation and emotion: a functional magnetic resonance imaging study

Chechlacz, M, Rotshtein, P, Klamer, S, Pressl, H, Porubska, K, Higgs, S, Booth, D, Abele, H, Birbaumer, N and Nouwen, A (2009) Diabetes dietary management alters responses to food pictures in brain regions associated with motivation and emotion: a functional magnetic resonance imaging study. Diabetologia, 52 (3). pp. 524-533. ISSN 0012-186X

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Abstract

Aims/hypothesis
We hypothesised that living with type 2 diabetes would enhance responses to pictures of foods in brain regions known to be involved in learnt food sensory motivation and that these stronger activations would relate to scores for dietary adherence in diabetes and to measures of potential difficulties in adherence.

Methods
We compared brain responses to food images of 11 people with type 2 diabetes and 12 healthy control participants, matched for age and weight, using functional magnetic resonance imaging (fMRI).

Results
Having type 2 diabetes increased responses to pictured foods in the insula, orbitofrontal cortex (OFC) and basal ganglia and, within these regions, the effect of the fat content of the foods was larger in participants with type 2 diabetes than in healthy controls. Furthermore, increased activation to food within the insula and OFC positively correlated with external eating, dietary self-efficacy and dietary self-care. In contrast, responses within subcortical structures (amygdala and basal ganglia) were positively correlated with emotional eating and rated appetite for the food stimuli and negatively correlated with dietary self-care.

Conclusions/interpretation
Type 2 diabetes is associated with changes in brain responses to food that are modulated by dietary self-care. We propose that this is linked to the need to follow a life-long restrictive diet

Item Type: Article
Schools and Departments: School of Psychology > Psychology
Subjects: B Philosophy. Psychology. Religion > BF Psychology > BF0636 Applied psychology
R Medicine > R Medicine (General) > R726.5 Medicine and disease in relation to psychology. Terminal care.
R Medicine > RC Internal medicine > RC0321 Neurosciences. Biological psychiatry. Neuropsychiatry
T Technology > TX Home economics > TX0341 Nutrition. Foods and food supply
Depositing User: prof. David Booth
Date Deposited: 02 Feb 2015 07:58
Last Modified: 05 Feb 2015 15:41
URI: http://sro.sussex.ac.uk/id/eprint/52655
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