The effect of storage conditions on the physical stability of tablets

Nokhodchi, Ali and Javadzadeh, Yousef (2007) The effect of storage conditions on the physical stability of tablets. Pharmaceutical Technology Europe, 19 (1). pp. 20-26. ISSN 1753-7967

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Abstract

This article reviews the effect of moisture on the postcompaction properties of pharmaceutical solid dosage forms. It was stated that the amount of moisture adsorbed by drugs or excipients influences hardness, disintegration time of compacts and the dissolution rate of drugs. These changes may alter bioavailability and therapeutic efficacy, even though the drug potency and purity appear unaltered.

Item Type: Article
Schools and Departments: School of Life Sciences > Chemistry
Subjects: Q Science > QD Chemistry
Related URLs:
Depositing User: Head of School Life Sciences
Date Deposited: 07 Jan 2015 09:36
Last Modified: 07 Jan 2015 09:36
URI: http://sro.sussex.ac.uk/id/eprint/51731
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