A fluorescence lifetime extraction algorithm based on multiple signal classification

Yu, Hongqi and Li, David Day-Uei (2015) A fluorescence lifetime extraction algorithm based on multiple signal classification. Electronics Letters, 51 (1). pp. 81-83. ISSN 0013-5194

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Abstract

The multiple signal classification algorithm has been widely used in array signal processing for direction-of-arrival estimations. In this paper, we applied this algorithm to estimate fluorescence lifetimes for fluorescence lifetime imaging microscopy (FLIM) for the first time to our knowledge. Monte Carlo simulations were carried out to test its performances in comparison with the previously reported integral equation method, center-of-mass method and phasor method. Simulation results show that the proposed algorithm can achieve comparable or better results than the others. More importantly, it can easily resolve multi-exponential decays.

Item Type: Article
Schools and Departments: School of Engineering and Informatics > Engineering and Design
Subjects: T Technology > T Technology (General) > T0010 Communication of technical information
Depositing User: David Day-Uei Li
Date Deposited: 02 Dec 2014 13:07
Last Modified: 08 Mar 2017 08:55
URI: http://sro.sussex.ac.uk/id/eprint/51559

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