Diagnosis of childhood tuberculosis and host RNA expression in Africa

Anderson, Suzanne T, Kaforou, Myrsini, Brent, Andrew J, Wright, Victoria J, Banwell, Claire M, Chagaluka, George, Crampin, Amelia C, Dockrell, Hazel M, French, Neil, Hamilton, Melissa S, Hibberd, Martin L, Kern, Florian, Langford, Paul R, Ling, Ling, Mlotha, Rachel, Ottenhoff, Tom H M, Pienaar, Sandy, Pillay, Vashini, Scott, J Anthony G, Twahir, Hemed, Wilkinson, Robert J, Coin, Lachlan J, Heyderman, Robert S, Levin, Michael and Eley, Brian (2014) Diagnosis of childhood tuberculosis and host RNA expression in Africa. New England Journal of Medicine, 370 (18). pp. 1712-1723. ISSN 0028-4793

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Abstract

Improved diagnostic tests for tuberculosis in children are needed. We hypothesized that transcriptional signatures of host blood could be used to distinguish tuberculosis from other diseases in African children who either were or were not infected with the human immunodeficiency virus (HIV)

Item Type: Article
Schools and Departments: Brighton and Sussex Medical School > Clinical and Experimental Medicine
Subjects: R Medicine
Depositing User: Sandy Gray
Date Deposited: 02 Jul 2014 07:35
Last Modified: 14 Mar 2017 00:11
URI: http://sro.sussex.ac.uk/id/eprint/49144

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